抑郁症与在英国一家艾滋病诊所就诊的艾滋病病毒感染者自我报告的抗逆转录病毒疗法依从性差有关:一项横断面研究的结果。

IF 1.2 4区 医学 Q4 HEALTH POLICY & SERVICES
Jose Luis Paredes, Alejandro Arenas-Pinto, Connor McAlpine, Rebecca Matthews, Ana Milinkovic, Emmi Suonpera
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引用次数: 0

摘要

尽管最近在努力改善患者的心理健康,但在英国的艾滋病病毒感染者中抑郁症的发病率是否仍然很高,抑郁症是否与个人坚持抗逆转录病毒疗法有负面关系,这些都需要当代证据来评估。在对伦敦艾滋病病毒感染者的饮酒量和相关健康行为进行的横断面诊所调查的二次分析中,221 名受访者中有 106 人(48%)自述坚持抗逆转录病毒疗法的情况不佳(CASE 指数),69 人(31%)抑郁筛查呈阳性(PHQ-9)。与抑郁筛查呈阴性的受访者相比,自我报告抗逆转录病毒疗法依从性差的受访者比例高出 72%。更年轻、失业和报告有吸毒问题的受访者更有可能筛查出抑郁症阳性。将抑郁症筛查和管理作为常规艾滋病护理的一部分,可能有助于坚持抗逆转录病毒疗法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Depression is associated with poor self-reported adherence to antiretroviral therapy among people living with HIV attending an HIV clinic in the UK: results from a cross-sectional study.

Contemporary evidence is needed to assess whether the prevalence of depression remains high among people living with HIV in the United Kingdom despite recent efforts to improve patients' mental health, and if depression is negatively associated with individuals' adherence to antiretroviral therapy. In a secondary analysis of a cross-sectional clinic-based survey of alcohol consumption and associated health behaviour among people living with HIV in London, of the 221 respondents, 106 (48%) had poor self-reported adherence to antiretroviral therapy (CASE Index) and 69 (31%) screened positive for depression (PHQ-9). Poor self-reported adherence to ART was 72% higher among participants who screened positive for depression in comparison with participants who screened negative. Respondents who were younger, unemployed, and reported problematic drug use were more likely to screen positive for depression. Screening and management of depression as a part of routine HIV care may support adherence to antiretroviral therapy.

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