意识障碍的命名伦理问题

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-01-23 DOI:10.3233/nre-230120

Nathaniel M. Robbins MD, James L. Bernat MD

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引用次数: 0

摘要

目前对严重意识障碍（DoC）的分类方案有几个缺陷。首先，在如何纳入隐蔽意识障碍患者方面尚未达成共识。其次，以意识为基础的严重意识障碍定义与以可观察到的运动反应为基础的严重意识障碍诊断之间存在不匹配。第三，目前的分类归纳为多种不同的综合征，这些综合征具有相同的表型，但并不包含潜在的病理生理学。在此，我们讨论了与当前严重 DoC 命名相关的几个伦理问题。最后，我们将针对这些缺陷提出一个修订后的命名法。

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Ethical issues of nosology in disorders of consciousness

The current classification scheme for severe disorders of consciousness (DoC) has several shortcomings. First, there is no consensus on how to incorporate patients with covert consciousness. Second, there is a mismatch between the definitions of severe DoC, based on consciousness, and the diagnosisof these same DoC, which is based on observable motoric responsiveness. Third, current categories are grouped into large heterogeneous syndromes which share phenotype, but do not incorporate underlying pathophysiology. Here we discuss several ethical issues pertaining to the current nosology of severe DoC. We conclude by proposing a revised nosology which addresses these shortcomings.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.