与肢体残疾相比,抑郁对预测包涵体肌炎患者的健康状况更为重要。

Georgina Nunn, Genevieve Glenister, Kathryn Hird, Kelly Beer, Ian Cooper, Merrilee Needham
{"title":"与肢体残疾相比,抑郁对预测包涵体肌炎患者的健康状况更为重要。","authors":"Georgina Nunn, Genevieve Glenister, Kathryn Hird, Kelly Beer, Ian Cooper, Merrilee Needham","doi":"10.1101/2024.01.22.24301628","DOIUrl":null,"url":null,"abstract":"Objectives: (1) determine if there is a correlation between disability, depression, and wellbeing in people with IBM, (2) determine if disability and depression can predict wellbeing in people with IBM, and (3) identify the prevalence of depression and impaired wellbeing in participants with IBM.\nMethods: In this cross-sectional study, 101 participants with IBM completed the Neuromuscular Symptom Score (NSS), Personal Wellbeing Index (PWI), and Patient Health Questionnaire-9 (PHQ-9) surveys to serve as surrogate measures of physical disability, wellbeing, and depression respectively.\nResults: Linear regression identified that PHQ-9 significantly predicts PWI, however NSS does not, with a negative predictive value of depression for wellbeing (-2.7513, p < 0.001) and a positive predictive value of disability for wellbeing (0.0575, p = 0.764). Moderate to severe depression was reported in 78.2% of participants, and all but one participant reported reduced wellbeing.\nConclusions: Depression is a more significant predictor of wellbeing than disability in participants diagnosed with IBM. There was a high prevalence of depression and reduced wellbeing in participants, highlighting the importance of assessing these factors to optimise treatment in IBM.","PeriodicalId":501212,"journal":{"name":"medRxiv - Rheumatology","volume":"4 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Depression is a more significant predictor for wellbeing in Inclusion Body Myositis than physical disability.\",\"authors\":\"Georgina Nunn, Genevieve Glenister, Kathryn Hird, Kelly Beer, Ian Cooper, Merrilee Needham\",\"doi\":\"10.1101/2024.01.22.24301628\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objectives: (1) determine if there is a correlation between disability, depression, and wellbeing in people with IBM, (2) determine if disability and depression can predict wellbeing in people with IBM, and (3) identify the prevalence of depression and impaired wellbeing in participants with IBM.\\nMethods: In this cross-sectional study, 101 participants with IBM completed the Neuromuscular Symptom Score (NSS), Personal Wellbeing Index (PWI), and Patient Health Questionnaire-9 (PHQ-9) surveys to serve as surrogate measures of physical disability, wellbeing, and depression respectively.\\nResults: Linear regression identified that PHQ-9 significantly predicts PWI, however NSS does not, with a negative predictive value of depression for wellbeing (-2.7513, p < 0.001) and a positive predictive value of disability for wellbeing (0.0575, p = 0.764). Moderate to severe depression was reported in 78.2% of participants, and all but one participant reported reduced wellbeing.\\nConclusions: Depression is a more significant predictor of wellbeing than disability in participants diagnosed with IBM. There was a high prevalence of depression and reduced wellbeing in participants, highlighting the importance of assessing these factors to optimise treatment in IBM.\",\"PeriodicalId\":501212,\"journal\":{\"name\":\"medRxiv - Rheumatology\",\"volume\":\"4 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Rheumatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.01.22.24301628\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Rheumatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.01.22.24301628","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

目的:(1) 确定 IBM 患者的残疾、抑郁和幸福感之间是否存在相关性;(2) 确定残疾和抑郁是否可以预测 IBM 患者的幸福感;(3) 确定 IBM 患者中抑郁和幸福感受损的发生率:在这项横断面研究中,101 名 IBM 患者完成了神经肌肉症状评分(NSS)、个人幸福指数(PWI)和患者健康问卷-9(PHQ-9)调查,分别作为身体残疾、幸福和抑郁的替代测量指标:线性回归结果表明,PHQ-9 能显著预测 PWI,但 NSS 不能,抑郁对健康的预测值为负数(-2.7513,p < 0.001),残疾对健康的预测值为正数(0.0575,p = 0.764)。78.2%的参与者患有中度至重度抑郁症,除一名参与者外,其他参与者均表示幸福感下降:结论:在被诊断为 IBM 的参与者中,抑郁是比残疾更重要的幸福预测因素。参与者中抑郁和幸福感降低的发生率很高,这突出了评估这些因素对优化 IBM 治疗的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Depression is a more significant predictor for wellbeing in Inclusion Body Myositis than physical disability.
Objectives: (1) determine if there is a correlation between disability, depression, and wellbeing in people with IBM, (2) determine if disability and depression can predict wellbeing in people with IBM, and (3) identify the prevalence of depression and impaired wellbeing in participants with IBM. Methods: In this cross-sectional study, 101 participants with IBM completed the Neuromuscular Symptom Score (NSS), Personal Wellbeing Index (PWI), and Patient Health Questionnaire-9 (PHQ-9) surveys to serve as surrogate measures of physical disability, wellbeing, and depression respectively. Results: Linear regression identified that PHQ-9 significantly predicts PWI, however NSS does not, with a negative predictive value of depression for wellbeing (-2.7513, p < 0.001) and a positive predictive value of disability for wellbeing (0.0575, p = 0.764). Moderate to severe depression was reported in 78.2% of participants, and all but one participant reported reduced wellbeing. Conclusions: Depression is a more significant predictor of wellbeing than disability in participants diagnosed with IBM. There was a high prevalence of depression and reduced wellbeing in participants, highlighting the importance of assessing these factors to optimise treatment in IBM.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信