治疗艾滋病毒阳性患者慢性种植体周围炎的经验

M. A. Morozov, A. K. Iordanishvili, A. Serikov
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摘要

相关性。有关治疗 HIV 阳性患者慢性种植体周围炎的数据很少。完善现有的牙科种植体周围炎症治疗技术具有重要意义,尤其是对艾滋病病毒感染者而言。因此,本研究旨在总结治疗 HIV 阳性患者慢性种植体周围炎的临床经验。研究涉及六名男性患者(治疗组),年龄在 35 至 54 岁之间,被诊断为慢性种植体周围炎,表现为种植体周围炎症,HIV 检测呈阳性。这些患者接受传染病专家的动态观察,并持续接受抗逆转录病毒治疗。对照组由 10 名男性组成,年龄在 28 至 55 岁之间,没有感染艾滋病毒,也没有任何其他导致继发性免疫缺陷的疾病。他们接受了口腔微生物群和粘膜免疫检查,并接受了慢性种植体周围炎治疗。两组患者均已种植牙 5 至 7 年。结果。种植体周围炎的 HIV 阳性患者表现出微生物群和粘膜免疫的改变,这与 "病毒载量 "指标相关。该研究介绍了牙周炎的综合治疗结果以及调整后的抗逆转录病毒疗法对粘膜免疫和口腔微生物群参数的影响。在口腔卫生良好的艾滋病病毒阳性患者中,种植体周围炎的发病可能与抗逆转录病毒治疗无效的潜在因素有关。因此,在诊断艾滋病病毒阳性患者的种植体周围炎时,不仅要采取适当的治疗和预防措施,将其作为种植体周围炎综合治疗方案的一部分,同时以专业方式进行精确的口腔卫生矫正,还要及时转诊至传染病专科医生,以调整抗逆转录病毒疗法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The experience of treating chronic peri-implantitis in HIV positive patients
Relevance. There is a scarcity of data regarding the treatment of chronic peri-implantitis in HIV-positive patients. The refinement of available techniques for managing inflammation around dental implants holds significant importance, particularly in individuals infected with HIV. Hence, this study aims to consolidate clinical experiences in managing chronic peri-implantitis in HIV-positive patients.Materials and methods. The study involved six male patients (treatment group), aged 35 to 54, diagnosed with chronic peri-implantitis, exhibiting inflammation around dental implants and testing HIV positive. These patients, under dynamic observation by their infectious disease specialist, were consistently receiving antiretroviral treatment. The control group consisted of 10 males aged 28 to 55, devoid of HIV or any other condition causing secondary immunodeficiency. Oral cavity microbiota and mucosal immunity were examined, and treatment for chronic peri-implantitis was administered. Both groups had dental implants for 5 to 7 years. The specifics of the implantation systems were not explored.Results. HIV-positive patients with peri-implantitis exhibited alterations in microbiota and mucosal immunity, correlating with "viral load" indicators. The study presented combined treatment outcomes for periodontitis and the influence of adjusted antiretroviral therapy on mucosal immunity and oral cavity microbiota parameters.Conclusion. Peri-implantitis onset in HIV-positive patients with adequate oral hygiene might be linked to an underlying factor involving ineffective administration of antiretroviral treatment. Consequently, diagnosing periimplantitis in HIV-positive individuals should not only entail appropriate therapeutic and preventive measures as part of a comprehensive peri-implantitis treatment regimen, along with precise oral hygiene correction performed professionally, but also timely referral to an infectious disease specialist for adjustment of antiretroviral therapy.
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