{"title":"基于横断面研究和双向孟德尔随机法的膳食维生素 C 摄入水平与高尿酸血症和痛风风险分析","authors":"Zi-Ning Peng, Xing-Qiang Wang, Qian Deng, Wei-Tian Yan, Wei-Qing Zhao, Yong-Bin Pu, Nian Liu, Ling-Li Gu, Jiang-Yun Peng","doi":"10.1101/2024.01.18.24301481","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Vitamin C, a common antioxidant, may be useful for treating hyperuricemia and gout. The aim of this study was to investigate the risk association between dietary vitamin C intake and hyperuricemia/gout and to test for causality using the bi-directional Mendelian randomisation method.","PeriodicalId":501212,"journal":{"name":"medRxiv - Rheumatology","volume":"175 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analysis of dietary vitamin C intake levels and the risk of hyperuricemia and gout based on cross-sectional studies and bi-directional Mendelian randomisation\",\"authors\":\"Zi-Ning Peng, Xing-Qiang Wang, Qian Deng, Wei-Tian Yan, Wei-Qing Zhao, Yong-Bin Pu, Nian Liu, Ling-Li Gu, Jiang-Yun Peng\",\"doi\":\"10.1101/2024.01.18.24301481\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<strong>Background</strong> Vitamin C, a common antioxidant, may be useful for treating hyperuricemia and gout. The aim of this study was to investigate the risk association between dietary vitamin C intake and hyperuricemia/gout and to test for causality using the bi-directional Mendelian randomisation method.\",\"PeriodicalId\":501212,\"journal\":{\"name\":\"medRxiv - Rheumatology\",\"volume\":\"175 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Rheumatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.01.18.24301481\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Rheumatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.01.18.24301481","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景 维生素 C 是一种常见的抗氧化剂，可用于治疗高尿酸血症和痛风。本研究旨在调查膳食中维生素 C 摄入量与高尿酸血症/痛风之间的风险关联，并采用双向孟德尔随机法检验因果关系。
Analysis of dietary vitamin C intake levels and the risk of hyperuricemia and gout based on cross-sectional studies and bi-directional Mendelian randomisation
Background Vitamin C, a common antioxidant, may be useful for treating hyperuricemia and gout. The aim of this study was to investigate the risk association between dietary vitamin C intake and hyperuricemia/gout and to test for causality using the bi-directional Mendelian randomisation method.
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