Kyle Reid, Lori-Ann R. Sacrey, Lonnie Zwaigenbaum, Jessica A. Brian, Isabel M. Smith
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引用次数: 0
摘要
婴儿自闭症观察量表 (AOSI) 目前正应用于非婴儿兄弟姐妹群体。因此，有必要对该工具在可能性增加（IL）人群中的实用性进行评估。我们对六个数据库中的 17 项研究进行了系统回顾和荟萃分析。AOSI 已在四种 IL 情况下使用：婴儿兄弟姐妹、脆性 X 综合征婴儿、结节性硬化综合征婴儿和唐氏综合征婴儿。主要发现有三点：（1）五项研究报告了分类数据，但没有使用一致的方法；（2）IL-ASD、IL 非 ASD 和对照组之间的群体差异始于 12 个月；（3）IL-ASD 和对照组样本之间的效应大小较大。结果表明，AOSI可用于识别IL人群中ASD的早期症状。
Autism Observation Scale for Infants: Systematic Review and Meta-Analysis in Samples at Increased Likelihood of Autism Spectrum Disorders
The Autism Observation Scale for Infants (AOSI) is being applied to non infant sibling populations. Assessment of the tool’s utility across increased likelihood (IL) populations is therefore needed. A systematic review and meta-analysis was conducted on 17 studies identified from six databases. The AOSI has been used in four IL contexts: infant siblings, infants with Fragile X Syndrome, Tuberous Sclerosis Complex, and Down Syndrome. There were three main findings: (1) five studies report classification data though no consistent approach was used; (2) group differences between IL-ASD, IL non-ASD, and controls started at 12-months; and (3) large effect sizes between IL-ASD and control samples was identified. Utility of the AOSI to identify early signs of ASD in IL populations was demonstrated.
期刊介绍：
The Review Journal of Autism and Developmental Disorders publishes original articles that provide critical reviews of topics across the broad interdisciplinary research fields of autism spectrum disorders. Topics range from basic to applied and include but are not limited to genetics, neuroscience, diagnosis, applied behavior analysis, psychopharmacology, incidence, prevalence, etiology, differential diagnosis, treatment, measurement of treatment effects, education, perception and cognition. Topics across the life span are appropriate. In addition, given the high rates of comorbid conditions, the interface of sleep disorders, feeding problems, motor difficulties, ADHD, anxiety, depression and other disorders with autism spectrum disorders are appropriate. The Journal aims for an international audience as reflected in the editorial board.
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