Xin Liu , Xinyue Zhou , Xiaocong Zhang , Lingling Sun , Guangdan Zhao , Shitao Mao , Fangzhi Li , Xiu Gu , Paul J. Wolters , Shuo Liu
{"title":"伴有支气管溃疡的侵袭性肺粘液腺癌 - 感染 SARS-CoV-2 后痰量明显减少","authors":"Xin Liu , Xinyue Zhou , Xiaocong Zhang , Lingling Sun , Guangdan Zhao , Shitao Mao , Fangzhi Li , Xiu Gu , Paul J. Wolters , Shuo Liu","doi":"10.1016/j.rmcr.2024.101982","DOIUrl":null,"url":null,"abstract":"<div><p>Bronchorrhea is a watery sputum volume of at least 100 mL/day, which is commonly associated with lung malignancies. We report a 57-year-old woman was admitted to the hospital with a cough, profuse sputum. Chest CTs showed crazy paving pattern and lung nodules. Cell nests were visible on the Thinprep Cytologic Test. The case was considered an invasive mucinous adenocarcinoma of the lung combined with bronchorrhea. Significantly, the sputum volume declined rapidly and did not rise again when the patient was diagnosed with COVID-19 and treated with nirmatrelvir/ritonavir. This case is suggestive of studies related to regulatory mediators associated with bronchorrhea.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"47 ","pages":"Article 101982"},"PeriodicalIF":0.8000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000054/pdfft?md5=b4c3c648b246ff3afbf8e71fd2ff6c3a&pid=1-s2.0-S2213007124000054-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection\",\"authors\":\"Xin Liu , Xinyue Zhou , Xiaocong Zhang , Lingling Sun , Guangdan Zhao , Shitao Mao , Fangzhi Li , Xiu Gu , Paul J. Wolters , Shuo Liu\",\"doi\":\"10.1016/j.rmcr.2024.101982\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Bronchorrhea is a watery sputum volume of at least 100 mL/day, which is commonly associated with lung malignancies. We report a 57-year-old woman was admitted to the hospital with a cough, profuse sputum. Chest CTs showed crazy paving pattern and lung nodules. Cell nests were visible on the Thinprep Cytologic Test. The case was considered an invasive mucinous adenocarcinoma of the lung combined with bronchorrhea. Significantly, the sputum volume declined rapidly and did not rise again when the patient was diagnosed with COVID-19 and treated with nirmatrelvir/ritonavir. This case is suggestive of studies related to regulatory mediators associated with bronchorrhea.</p></div>\",\"PeriodicalId\":51565,\"journal\":{\"name\":\"Respiratory Medicine Case Reports\",\"volume\":\"47 \",\"pages\":\"Article 101982\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2213007124000054/pdfft?md5=b4c3c648b246ff3afbf8e71fd2ff6c3a&pid=1-s2.0-S2213007124000054-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Respiratory Medicine Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2213007124000054\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respiratory Medicine Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213007124000054","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection
Bronchorrhea is a watery sputum volume of at least 100 mL/day, which is commonly associated with lung malignancies. We report a 57-year-old woman was admitted to the hospital with a cough, profuse sputum. Chest CTs showed crazy paving pattern and lung nodules. Cell nests were visible on the Thinprep Cytologic Test. The case was considered an invasive mucinous adenocarcinoma of the lung combined with bronchorrhea. Significantly, the sputum volume declined rapidly and did not rise again when the patient was diagnosed with COVID-19 and treated with nirmatrelvir/ritonavir. This case is suggestive of studies related to regulatory mediators associated with bronchorrhea.