嵌段共聚物稳定的金属有机框架杂化物负载钯纳米粒子，可通过近红外光热疗法缓解肿瘤症状

IF 4 Q2 ENGINEERING, BIOMEDICAL

Advanced Nanobiomed Research Pub Date : 2024-01-14 DOI:10.1002/anbr.202470011

Shang-Wei Li, Ming-Feng Hsieh, Taehun Hong, Pengwen Chen, Kensuke Osada, Xueying Liu, Ichio Aoki, Jiashing Yu, Kevin C.-W. Wu, Horacio Cabral

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引用次数: 0

摘要

光热疗法在编号为 2300107 的文章中，Jiashing Yu、Kevin C.-W.W.W.Wu、Horacio Cabral 及其合作者利用纳米级金属有机框架（MOF）在 MOF 结构中生成钯纳米粒子，以产生光热效应。Wu、Horacio Cabral 及合作者使用一种纳米级金属有机框架（MOF），在 MOF 结构中生成钯纳米粒子，以产生光热效应。钯纳米粒子的表面由生物相容性嵌段共聚物稳定，在近红外线照射下可增加肿瘤蓄积并缓解 B16F10 黑色素瘤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Block Copolymer-Stabilized Metal–Organic Framework Hybrids Loading Pd Nanoparticles Enable Tumor Remission Through Near-Infrared Photothermal Therapy

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Block Copolymer-Stabilized Metal–Organic Framework Hybrids Loading Pd Nanoparticles Enable Tumor Remission Through Near-Infrared Photothermal Therapy

Photothermal Therapy

In article number 2300107, Jiashing Yu, Kevin C.-W. Wu, Horacio Cabral, and co-workers use a nanosized metal–organic framework (MOF) to generate palladium nanoparticles within the MOF structure for producing photothermal effects. The palladium nanoparticles, having their surface stabilized with biocompatible block copolymers, achieve increased tumor accumulation and remission of B16F10 melanoma upon irradiation with near-infrared light.

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来源期刊

Advanced Nanobiomed Research nanomedicine, bioengineering and biomaterials-

CiteScore

5.00

自引率

5.90%

发文量

审稿时长

21 weeks

期刊介绍： Advanced NanoBiomed Research will provide an Open Access home for cutting-edge nanomedicine, bioengineering and biomaterials research aimed at improving human health. The journal will capture a broad spectrum of research from increasingly multi- and interdisciplinary fields of the traditional areas of biomedicine, bioengineering and health-related materials science as well as precision and personalized medicine, drug delivery, and artificial intelligence-driven health science. The scope of Advanced NanoBiomed Research will cover the following key subject areas: ▪ Nanomedicine and nanotechnology, with applications in drug and gene delivery, diagnostics, theranostics, photothermal and photodynamic therapy and multimodal imaging. ▪ Biomaterials, including hydrogels, 2D materials, biopolymers, composites, biodegradable materials, biohybrids and biomimetics (such as artificial cells, exosomes and extracellular vesicles), as well as all organic and inorganic materials for biomedical applications. ▪ Biointerfaces, such as anti-microbial surfaces and coatings, as well as interfaces for cellular engineering, immunoengineering and 3D cell culture. ▪ Biofabrication including (bio)inks and technologies, towards generation of functional tissues and organs. ▪ Tissue engineering and regenerative medicine, including scaffolds and scaffold-free approaches, for bone, ligament, muscle, skin, neural, cardiac tissue engineering and tissue vascularization. ▪ Devices for healthcare applications, disease modelling and treatment, such as diagnostics, lab-on-a-chip, organs-on-a-chip, bioMEMS, bioelectronics, wearables, actuators, soft robotics, and intelligent drug delivery systems. with a strong focus on applications of these fields, from bench-to-bedside, for treatment of all diseases and disorders, such as infectious, autoimmune, cardiovascular and metabolic diseases, neurological disorders and cancer; including pharmacology and toxicology studies.