利用蒙特卡洛 GATE 仿真对放射治疗应用中的根茎类模型材料进行剂量学分析。

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal of Medical Physics Pub Date : 2023-10-01 Epub Date: 2023-12-05 DOI:10.4103/jmp.jmp_75_23
Siti Hajar Zuber, Muhammad Fahmi Rizal Abdul Hadi, Damilola Oluwafemi Samson, Jayapramila Jayamani, Nor Ain Rabaiee, Mohd Zahri Abdul Aziz, Nurul Ab Aziz Hashikin, Chee Keat Ying, Mohd Fahmi Mohd Yusof, Rokiah Hashim
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引用次数: 0

摘要

目的:本研究旨在利用蒙特卡洛Geant4断层发射应用(GATE)模拟,确定由大豆-木质素粘合的Rhizophora spp.刨花板制成的光面涂层幻影材料的深度剂量百分比(PDD):刨花板采用热压技术制成,目标密度为 1.0 g-cm-3,并记录了用于模拟的元素组分。在 GATE 模拟中使用直线加速器 Elekta Synergy 模型对水模型和 Rhizophora 模型的 PDD 进行了模拟,并将结果与多项研究的实验 PDD 进行了比较。本研究还测量了光束平整度和光束对称性:Rhizophora 和水的模拟 PDD 与水的实验 PDD 一致,在 1.0 至 15.0 厘米的深度范围内,总体差异为 0% 至 8.7%。在 GATE 模拟中,与水相比,所有点都通过了临床 3%/3 mm 标准,最终 Rhizophora 模型的百分比为 2.34%,GATE 模拟的水模型的百分比为 2.49%。根据建议,这两个对称性都在 2.0% 的可接受值范围内,水模型和根瘤模型的光束对称性分别为 0.58% 和 0.28%:本研究的结果为放心地将模型用于放射治疗,尤其是治疗计划提供了必要的基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dosimetric Analysis of Rhizophora-based Phantom Material in Radiation Therapy Applications Using Monte Carlo GATE Simulation.

Purpose: This study aims to determine the percentage depth dose (PDD) of a phantom material made from soy-lignin bonded Rhizophora spp. particleboard coated with a gloss finish by using Monte Carlo Geant4 Application for Tomographic Emission (GATE) simulation.

Materials and methods: The particleboard was fabricated using a hot pressing technique at target density of 1.0 g·cm-3 and the elemental fraction was recorded for the simulation. The PDD was simulated in the GATE simulation using the linear accelerator Elekta Synergy model for the water phantom and Rhizophora phantom, and the results were compared with the experimental PDD performed by several studies. Beam flatness and beam symmetry were also measured in this study.

Results: The simulated PDD for Rhizophora and water was in agreement with the experimental PDD of water with overall discrepancies of 0% to 8.7% at depth ranging from 1.0 to 15.0 cm. In the GATE simulation, all the points passed the clinical 3%/3 mm criterion in comparison with water, with the final percentage of 2.34% for Rhizophora phantom and 2.49% for the water phantom simulated in GATE. Both the symmetries are all within the range of an acceptable value of 2.0% according to the recommendation, with the beam symmetry of the water phantom and Rhizophora phantom at 0.58% and 0.28%, respectively.

Conclusions: The findings of this study provide the necessary foundation to confidently use the phantom for radiotherapy purposes, especially in treatment planning.

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来源期刊
Journal of Medical Physics
Journal of Medical Physics RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.10
自引率
11.10%
发文量
55
审稿时长
30 weeks
期刊介绍: JOURNAL OF MEDICAL PHYSICS is the official journal of Association of Medical Physicists of India (AMPI). The association has been bringing out a quarterly publication since 1976. Till the end of 1993, it was known as Medical Physics Bulletin, which then became Journal of Medical Physics. The main objective of the Journal is to serve as a vehicle of communication to highlight all aspects of the practice of medical radiation physics. The areas covered include all aspects of the application of radiation physics to biological sciences, radiotherapy, radiodiagnosis, nuclear medicine, dosimetry and radiation protection. Papers / manuscripts dealing with the aspects of physics related to cancer therapy / radiobiology also fall within the scope of the journal.
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