慢性前列腺炎患者在复方类风湿因子和龙酶酶疗法影响下的生活质量

M. A. Mkrtchyan, B. Gusova, K. Emkuzhev, A. Kaisinova, Yu V Bobrik
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引用次数: 0

摘要

背景:在现代医学中,衡量治疗措施有效性的主要指标之一是患者的生活质量,它可以确定急性病治疗后身心健康的恢复程度。目的:根据对慢性细菌性前列腺炎患者生活质量的监测结果,评估使用长效酶的复合浴疗法和酶疗法的有效性。材料与方法:共观察了 54 名慢性前列腺炎患者。他们被简单随机分为两组:对比组(26 人)的患者接受运动疗法、热列兹诺沃茨克型矿泉水的内部和外部给药、硫化淤泥局部颗粒疗法、头孢曲松抗生素疗法、植物微量元素疗法;主要组(28 人)的患者通过外周间接淋巴疗法接受抗生素和酶疗法。疗效通过有效的生活质量问卷进行评估:慢性前列腺炎症状量表(NIH-CPS)和 SF-36 一般健康问卷(Social Functioning-36)。结果:对新治疗技术临床效果的分析表明,它比标准化疗法更有优势,这一点通过对水疗治疗后 1 年的 QoL 指标监测得到了证明:治疗后立即恢复 QoL 的主要组为 59.7% (P0.01),6 个月后为 72.7% (P0.01),12 个月后略有下降,为 64.9% (P0.01)。在 SF-36 量表中也观察到了身体和精神健康指标的动态变化,其可信度相同:与基线相比,平均改善率分别为 25.5%(P 0.01)、33.6%(P 0.01)和 27.3%(P 0.01)。在对比组中,所有 NIH-CPSI 和 SF-36 量表的指标动态变化也很显著,但比主要组的类似指标分别平均低 23%-25%(P 0.01)和 12%-15%。结论:研究结果表明,对处于水疗阶段的慢性前列腺炎患者进行复合浴疗法和淋巴疗法非常有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quality of life of the patients with chronic prostatitis under the influence of complex balneopeloid and enzyme therapy with Longidase
BACKGROUND: In modern medicine, among the main indicators of the effectiveness of therapeutic measures, the quality of life of the patient is singled out, which allows determining the degree of recovery of physical and mental health after treatment of acute conditions. AIM: to evaluate the effectiveness of complex balneopeloid and enzyme therapy with longidase according to the monitoring of the quality of life of the patients suffering from chronic bacterial prostatitis. MATERIALS AND METHODS: There have been observed 54 patients with chronic prostatitis. They were divided into 2 groups by simple randomization: in the comparison group (n=26) the patients were prescribed exercise therapy, internal and external administration of mineral water of Zheleznovodsk type, peloidotherapy with silt sulfide mud topically, antibiotic therapy with ceftriaxone, phytomicroclysters; in the main group (n=28), the patients additionally underwent antibiotic and enzyme therapy by peripheral indirect lymphotropic therapy. The efficiency was assessed using validated Quality of Life questionnaires: Chronic Prostatitis Symptom Scale (NIH-CPS) and SF-36 General Health Questionnaire (Social Functioning-36). RESULTS: The analysis of the clinical effect of the new treatment technology revealed its advantage over the standardized therapy, which is proven by the monitoring of QoL indicators for 1 year after the spa treatment: recovery of QoL in the main group immediately after the treatment occurred by 59.7% (p 0.01), 6 months later ― by 72.7% (p 0.01), with a slight decrease in the rate in 12 months ― by 64.9% (p 0.01). The dynamics of physical and mental health indicators on the SF-36 scale was also observed with the same degree of confidence: compared with the baseline, the average improvement was 25.5% (p 0.01), 33.6% (p 0.01) and 27.3% (p 0.01) respectively. In the comparison group, the dynamics of indicators for all NIH-CPSI and SF-36 scales was also significant, but lower than similar indicators in the main group by 23–25% on average (p 0.01) and 12–15%, respectively. CONCLUSION: The results of the study indicate the high effectiveness of complex balneopeloid and lymphotropic therapy with the patients suffering from chronic prostatitis at the stage of spa treatment.
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