农药暴露与农民中风风险因素生物标志物之间的关系

IF 0.8 Q4 CLINICAL NEUROLOGY
Ismail Setyopranoto, A. Panggabean, E. Dwianingsih, C. T. S. Setyaningrum, S. Sutarni, R. Malueka, Mawaddah Ar Rochmah
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引用次数: 0

摘要

杀虫剂的广泛使用可能导致急性和慢性中毒。因此,本研究旨在揭示农民农药暴露与中风危险因素血清标志物之间的关系。本研究对印度尼西亚中爪哇省 Magelang 县 Ngablak 区 Seloprojo 村使用化学农药的农民进行了横断面研究。问卷内容包括人口统计学、杀虫剂使用情况以及与工作相关的方面。此外,还对血清胆固醇、尿酸、葡萄糖、胆碱酯酶和纤维蛋白原水平进行了测量。在 106 名受试者中,有 31 人(29.2%)使用有机磷类化学杀虫剂。有机磷组和非有机磷组的血浆纤维蛋白原水平存在明显差异。有机磷组的纤维蛋白原水平(292.29 ± 67.56 mg/dL)高于非有机磷组(255.24 ± 38.90 mg/dL)。在所研究的中风风险因素中,有机磷暴露与血浆纤维蛋白原水平升高之间存在显著关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Associations between pesticide exposure with biomarkers of stroke risk factors in farmers
The extensive use of pesticides may cause acute and chronic intoxication. Therefore, this study aimed to reveal the associations between pesticide exposure and serum markers for stroke risk factors in farmers. A cross-sectional study was conducted with farmers, who used chemical pesticides in Seloprojo Village, Ngablak District, Magelang Regency, Central Java Province, Indonesia. A questionnaire containing demographics, pesticide use, and aspects related to work was employed. Measurements of serum cholesterol, uric acid, glucose, cholinesterase, and fibrinogen levels were also conducted. Of the 106 subjects, 31 (29.2%) used organophosphates as chemical pesticides. There was a significant difference between organophosphate and nonorganophosphate groups in plasma fibrinogen levels. The organophosphate group had higher levels of fibrinogen (292.29 ± 67.56 mg/dL) than the non-organophosphate group (255.24 ± 38.90 mg/dL). Of the studied risk factors for stroke, there is a significant association between organophosphate exposure and increased plasma fibrinogen levels.
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来源期刊
CiteScore
2.10
自引率
0.00%
发文量
129
审稿时长
22 weeks
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