结直肠癌患者 PD-L1 表达、临床病理因素与转移风险之间的相关性

IF 1.8 4区医学 Q3 HEALTH CARE SCIENCES & SERVICES

European Journal of Cancer Care Pub Date : 2024-01-08 DOI:10.1155/2024/5578953

Alireza Zarbakhsh, Amirreza Khalaji, Amir Vahedi, Roya Dolatkhah, Nasrin Gholami

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引用次数: 0

摘要

本研究调查了结直肠癌（CRC）患者中 PD-L1 表达、转移和生存之间的相关性。PD-L1 表达与总生存期、无病生存期或死亡率无明显相关性。不过，PD-L1 阳性和阴性患者在出现转移方面存在明显差异，PD-L1 阳性组的转移率更高。这些研究结果表明，PD-L1的表达可能会影响CRC患者的转移，但不会影响总生存率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Correlation between PD-L1 Expression, Clinicopathological Factors, and Metastasis Risk in Colorectal Cancer Patients

This study investigated the correlation between PD-L1 expression, metastasis, and survival in colorectal cancer (CRC) patients. PD-L1 expression was not significantly associated with overall survival, disease-free survival, or mortality rate. However, a significant difference was observed between PD-L1 positive and negative patients regarding the presence of metastasis, which was higher in the PD-L1 positive group. These findings suggest that PD-L1 expression may impact metastasis in CRC patients but not overall survival.

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来源期刊

European Journal of Cancer Care 医学-康复医学

CiteScore

4.00

自引率

4.80%

发文量

213

审稿时长

3 months

期刊介绍： The European Journal of Cancer Care aims to encourage comprehensive, multiprofessional cancer care across Europe and internationally. It publishes original research reports, literature reviews, guest editorials, letters to the Editor and special features on current issues affecting the care of cancer patients. The Editor welcomes contributions which result from team working or collaboration between different health and social care providers, service users, patient groups and the voluntary sector in the areas of: - Primary, secondary and tertiary care for cancer patients - Multidisciplinary and service-user involvement in cancer care - Rehabilitation, supportive, palliative and end of life care for cancer patients - Policy, service development and healthcare evaluation in cancer care - Psychosocial interventions for patients and family members - International perspectives on cancer care