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引用次数: 0
摘要
本文探讨了基于基因编辑(GE)的新兴技术在应对我们面临的全球挑战方面的应用范围。这些挑战涉及粮食安全、气候变化和生物多样性枯竭。本文特别探讨了应对这些挑战的最合适的农业生产形式背后的科学和证据、2022 年底商定的全球生物多样性框架(GBF)中设定的目标,以及基因编辑技术在促进实现这些目标方面可能发挥的作用。然后,本报告借鉴转基因生物 (GMO) 等其他农业和食品生产系统创新监管制度的影响经验,探讨了最有利于采用 GE 技术所需的风险最适当的监管环境。
Risk-appropriate regulations for gene-editing technologies.
This paper explores the scope for the newly emerging technologies, based on gene editing (GE) contributing to addressing the global challenges that we face. These challenges relate to food security, climate change and biodiversity depletion. In particular, it examines the science and evidence behind the most appropriate forms of agricultural production to meet these challenges, the targets set in the Global Biodiversity Framework (GBF) agreed to at the end of 2022 and the possible role of GE technologies in contributing to meeting these targets. It then examines the most risk-appropriate regulatory environment required to best facilitate the adoption of GE technology, drawing on the experiences of the impact of regulatory systems for other innovations used in agricultural and food production systems such as genetically modified organisms (GMOs).
期刊介绍:
GM Crops & Food - Biotechnology in Agriculture and the Food Chain aims to publish high quality research papers, reviews, and commentaries on a wide range of topics involving genetically modified (GM) crops in agriculture and genetically modified food. The journal provides a platform for research papers addressing fundamental questions in the development, testing, and application of transgenic crops. The journal further covers topics relating to socio-economic issues, commercialization, trade and societal issues. GM Crops & Food aims to provide an international forum on all issues related to GM crops, especially toward meaningful communication between scientists and policy-makers.
GM Crops & Food will publish relevant and high-impact original research with a special focus on novelty-driven studies with the potential for application. The journal also publishes authoritative review articles on current research and policy initiatives, and commentary on broad perspectives regarding genetically modified crops. The journal serves a wide readership including scientists, breeders, and policy-makers, as well as a wider community of readers (educators, policy makers, scholars, science writers and students) interested in agriculture, medicine, biotechnology, investment, and technology transfer.
Topics covered include, but are not limited to:
• Production and analysis of transgenic crops
• Gene insertion studies
• Gene silencing
• Factors affecting gene expression
• Post-translational analysis
• Molecular farming
• Field trial analysis
• Commercialization of modified crops
• Safety and regulatory affairs
BIOLOGICAL SCIENCE AND TECHNOLOGY
• Biofuels
• Data from field trials
• Development of transformation technology
• Elimination of pollutants (Bioremediation)
• Gene silencing mechanisms
• Genome Editing
• Herbicide resistance
• Molecular farming
• Pest resistance
• Plant reproduction (e.g., male sterility, hybrid breeding, apomixis)
• Plants with altered composition
• Tolerance to abiotic stress
• Transgenesis in agriculture
• Biofortification and nutrients improvement
• Genomic, proteomic and bioinformatics methods used for developing GM cops
ECONOMIC, POLITICAL AND SOCIAL ISSUES
• Commercialization
• Consumer attitudes
• International bodies
• National and local government policies
• Public perception, intellectual property, education, (bio)ethical issues
• Regulation, environmental impact and containment
• Socio-economic impact
• Food safety and security
• Risk assessments