{"title":"大分子结构对两亲性 AB 型嵌段共聚物溶液自组装的影响","authors":"Naoki Ozawa , Tomoki Nishimura","doi":"10.1039/d3py01324c","DOIUrl":null,"url":null,"abstract":"<div><p>Polymers with different architectures, such as block, graft, star, and cyclic polymers, have been developed owing to recent advances in synthetic technology. Notably, minor changes in the architecture of amphiphilic polymers can lead to different self-assembly behaviors, even when their molecular weights and hydrophilic–hydrophobic compositions are similar. This variation in the self-assembly behavior directly affects the properties and performance of self-assembled polymer-based materials. However, a clear understanding of how changes in polymer architecture influence self-assembly behavior is still emerging. This review aims to compare the self-assembly behaviors of amphiphilic AB-type block copolymers with different molecular architectures and elucidate how different polymer architectures influence self-assembly behaviors, as well as their underlying mechanisms. The discussion extends to recent applications, demonstrating how changes in polymer architecture can influence the performance of polymer assemblies used as carriers in drug delivery systems.</p></div>","PeriodicalId":100,"journal":{"name":"Polymer Chemistry","volume":"15 5","pages":"Pages 349-370"},"PeriodicalIF":3.9000,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Macromolecular architectural effects on solution self-assembly of amphiphilic AB-type block copolymers\",\"authors\":\"Naoki Ozawa , Tomoki Nishimura\",\"doi\":\"10.1039/d3py01324c\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Polymers with different architectures, such as block, graft, star, and cyclic polymers, have been developed owing to recent advances in synthetic technology. Notably, minor changes in the architecture of amphiphilic polymers can lead to different self-assembly behaviors, even when their molecular weights and hydrophilic–hydrophobic compositions are similar. This variation in the self-assembly behavior directly affects the properties and performance of self-assembled polymer-based materials. However, a clear understanding of how changes in polymer architecture influence self-assembly behavior is still emerging. This review aims to compare the self-assembly behaviors of amphiphilic AB-type block copolymers with different molecular architectures and elucidate how different polymer architectures influence self-assembly behaviors, as well as their underlying mechanisms. The discussion extends to recent applications, demonstrating how changes in polymer architecture can influence the performance of polymer assemblies used as carriers in drug delivery systems.</p></div>\",\"PeriodicalId\":100,\"journal\":{\"name\":\"Polymer Chemistry\",\"volume\":\"15 5\",\"pages\":\"Pages 349-370\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2024-01-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polymer Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S1759995424000275\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"POLYMER SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polymer Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1759995424000275","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 0
摘要
随着合成技术的不断进步,人们开发出了具有不同结构的聚合物,如嵌段、接枝、星形和环形聚合物。值得注意的是,即使两亲性聚合物的分子量和亲水-疏水成分相似,其结构的细微变化也会导致不同的自组装行为。自组装行为的这种变化会直接影响自组装聚合物基材料的特性和性能。然而,对于聚合物结构的变化如何影响自组装行为的清晰认识仍在形成之中。本综述旨在比较具有不同分子结构的两亲 AB 型嵌段共聚物的自组装行为,阐明不同聚合物结构如何影响自组装行为及其内在机理。讨论延伸到最近的应用,展示了聚合物结构的变化如何影响用作药物输送系统载体的聚合物组装体的性能。
Macromolecular architectural effects on solution self-assembly of amphiphilic AB-type block copolymers
Polymers with different architectures, such as block, graft, star, and cyclic polymers, have been developed owing to recent advances in synthetic technology. Notably, minor changes in the architecture of amphiphilic polymers can lead to different self-assembly behaviors, even when their molecular weights and hydrophilic–hydrophobic compositions are similar. This variation in the self-assembly behavior directly affects the properties and performance of self-assembled polymer-based materials. However, a clear understanding of how changes in polymer architecture influence self-assembly behavior is still emerging. This review aims to compare the self-assembly behaviors of amphiphilic AB-type block copolymers with different molecular architectures and elucidate how different polymer architectures influence self-assembly behaviors, as well as their underlying mechanisms. The discussion extends to recent applications, demonstrating how changes in polymer architecture can influence the performance of polymer assemblies used as carriers in drug delivery systems.
期刊介绍:
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.