Ahmed El-Sehemy, Isabela Martins Melo, Aurora Pecaku, Chris Zajner, Sumana Naidu, Yasmin Motekalem, Rajeev H Muni
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Increasing baseline morphologic stage of RRD was significantly associated with external limiting membrane, ellipsoid zone, and interdigitation zone discontinuity at all time points postoperatively ( P < 0.001) and was shown to be an independent predictor of foveal photoreceptor integrity after adjusting for height of detachment, time to surgery, and duration of fovea involvement ( P < 0.001). Earlier stages were associated with residual subfoveal fluid ( P < 0.001). There was no association between the stages of RRD and epiretinal membrane severity. However, late stages presented with earlier development of epiretinal membrane ( P = 0.012).</p><p><strong>Conclusion: </strong>Increasing morphologic stage of RRD is associated with delayed recovery of outer retinal bands in the first year and faster development of epiretinal membrane after RRD repair. The results of this study suggest that the stages may serve as a prognostic biomarker for postoperative photoreceptor recovery.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"POSTOPERATIVE PHOTORECEPTOR INTEGRITY AND ANATOMICAL OUTCOMES BASED ON PRESENTING MORPHOLOGIC STAGE OF RHEGMATOGENOUS RETINAL DETACHMENT.\",\"authors\":\"Ahmed El-Sehemy, Isabela Martins Melo, Aurora Pecaku, Chris Zajner, Sumana Naidu, Yasmin Motekalem, Rajeev H Muni\",\"doi\":\"10.1097/IAE.0000000000004034\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To evaluate outer retinal recovery on postoperative optical coherence tomography (OCT) based on presenting morphologic stage of rhegmatogenous retinal detachment (RRD).</p><p><strong>Methods: </strong>Retrospective cohort of consecutive primary fovea-involving RRDs, referred from January 2012 to September 2022. 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引用次数: 0
摘要
目的:根据流变性视网膜脱离(RRD)的形态学阶段,评估术后光学相干断层扫描(OCT)的外层视网膜恢复情况:2012年1月至2022年9月期间转诊的连续原发性眼窝牵涉型RRD的回顾性队列。对基线 OCT 进行评估,以确定 RRD 的形态分期。术后3个月、6个月和12个月的OCT对外缘膜(ELM)、椭圆形区(EZ)和连接区(IDZ)的不连续性、视网膜外膜(ERM)的形成和严重程度以及残留的眼底积液进行分级:共纳入 351 名患者。RRD基线形态分期的增加与ELM、EZ和IDZ在术后所有时间点的不连续性均有显著相关性(p结论:RRD基线形态分期的增加与ELM、EZ和IDZ在术后所有时间点的不连续性均有显著相关性:RRD形态分期的增加与第一年视网膜外带的延迟恢复和RRD修复后ERM的快速发展有关。我们的研究结果表明,分期可作为术后感光器恢复的预后生物标志物。
POSTOPERATIVE PHOTORECEPTOR INTEGRITY AND ANATOMICAL OUTCOMES BASED ON PRESENTING MORPHOLOGIC STAGE OF RHEGMATOGENOUS RETINAL DETACHMENT.
Purpose: To evaluate outer retinal recovery on postoperative optical coherence tomography (OCT) based on presenting morphologic stage of rhegmatogenous retinal detachment (RRD).
Methods: Retrospective cohort of consecutive primary fovea-involving RRDs, referred from January 2012 to September 2022. Baseline OCTs were assessed for morphologic stage of RRD. Postoperative OCT scans were graded at 3, 6, and 12 months for external limiting membrane, ellipsoid zone and interdigitation zone discontinuity, epiretinal membrane formation and severity, and residual subfoveal fluid.
Results: Three hundred and fifty-one patients were included. Increasing baseline morphologic stage of RRD was significantly associated with external limiting membrane, ellipsoid zone, and interdigitation zone discontinuity at all time points postoperatively ( P < 0.001) and was shown to be an independent predictor of foveal photoreceptor integrity after adjusting for height of detachment, time to surgery, and duration of fovea involvement ( P < 0.001). Earlier stages were associated with residual subfoveal fluid ( P < 0.001). There was no association between the stages of RRD and epiretinal membrane severity. However, late stages presented with earlier development of epiretinal membrane ( P = 0.012).
Conclusion: Increasing morphologic stage of RRD is associated with delayed recovery of outer retinal bands in the first year and faster development of epiretinal membrane after RRD repair. The results of this study suggest that the stages may serve as a prognostic biomarker for postoperative photoreceptor recovery.
期刊介绍:
RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice.
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