细胞自噬与内体囊泡贩运的相互联系及其在乙型肝炎病毒复制和释放中的作用

IF 5.5 3区 医学 Q1 Medicine
Jia Li , Yong Lin , Xueyu Wang , Mengji Lu
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引用次数: 0

摘要

乙型肝炎病毒(HBV)会产生和释放各种类型的颗粒,包括完整的病毒颗粒、带有包膜蛋白的亚病毒颗粒和裸盖体。最近的研究表明,HBV利用不同的细胞膜内转运途径(包括内膜囊泡转运和自噬途径)来组装和释放病毒颗粒和亚病毒颗粒。在此,我们总结了自噬和内体膜贩运的不同作用以及这两种途径在 HBV 复制、组装和释放过程中的相互作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Interconnection of cellular autophagy and endosomal vesicle trafficking and its role in hepatitis B virus replication and release

Hepatitis B virus (HBV) produces and releases various particle types, including complete virions, subviral particles with envelope proteins, and naked capsids. Recent studies demonstrate that HBV exploits distinct intracellular membrane trafficking pathways, including the endosomal vesicle trafficking and autophagy pathway, to assemble and release viral and subviral particles. Herein, we summarize the findings about the distinct roles of autophagy and endosomal membrane trafficking and the interaction of both pathways in HBV replication, assembly, and release.

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来源期刊
Virologica Sinica
Virologica Sinica Biochemistry, Genetics and Molecular Biology-Molecular Medicine
CiteScore
7.70
自引率
1.80%
发文量
3149
期刊介绍: Virologica Sinica is an international journal which aims at presenting the cutting-edge research on viruses all over the world. The journal publishes peer-reviewed original research articles, reviews, and letters to the editor, to encompass the latest developments in all branches of virology, including research on animal, plant and microbe viruses. The journal welcomes articles on virus discovery and characterization, viral epidemiology, viral pathogenesis, virus-host interaction, vaccine development, antiviral agents and therapies, and virus related bio-techniques. Virologica Sinica, the official journal of Chinese Society for Microbiology, will serve as a platform for the communication and exchange of academic information and ideas in an international context. Electronic ISSN: 1995-820X; Print ISSN: 1674-0769
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