在戒断期间发病的大麻诱发精神障碍：新证据简要报告。

IF 2.6 4区医学 Q3 NEUROSCIENCES

Acta Neuropsychiatrica Pub Date : 2024-01-11 DOI:10.1017/neu.2023.60

Johan Cohen, Hugues Petitjean, M Belen Blasco, Romina Mizrahi

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引用次数: 0

摘要

目的：吸食大麻与精神病症状或精神障碍之间的关系众所周知。然而，有关大麻戒断与精神病症状之间关系的研究却较少：据我们所知，这是首次发表关于在戒断期间发病的大麻诱发精神病性障碍的观察性系统报告。在此，我们回顾了 2020 年 1 月至 2023 年 9 月期间因戒除大麻后出现精神病症状而前往蒙特利尔一家大型急诊室就诊的患者：7名男性和1名女性患者在大麻戒断高峰期出现急性精神病症状，占所有急诊入院患者的不到1%：我们讨论了目前有关内源性大麻素系统和多巴胺平衡的知识，并就这些观察结果提出了假设。

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Cannabis-induced psychotic disorder with onset during withdrawal: a brief report of emerging evidence.

Objectives: The link between cannabis use and psychotic symptoms or disorders is well known. However, the relation between cannabis withdrawal and psychotic symptoms is less studied.

Methods: To our knowledge, this is the first publication of an observational systematic report of cannabis-induced psychotic disorder with onset during withdrawal. Here, we review patients presenting to a major emergency room in Montreal between January 2020 and September 2023 in a context of psychotic symptoms following cannabis cessation.

Results: In total, seven male and one female patients presented at the peak of cannabis withdrawal with acute psychotic symptoms, representing less than 1% of all emergency service admissions.

Conclusions: We discuss current knowledge regarding the endocannabinoid system and dopamine homeostasis to formulate hypotheses regarding these observations.

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来源期刊

Acta Neuropsychiatrica NEUROSCIENCES-PSYCHIATRY

自引率

5.30%

发文量

期刊介绍： Acta Neuropsychiatrica is an international journal focussing on translational neuropsychiatry. It publishes high-quality original research papers and reviews. The Journal''s scope specifically highlights the pathway from discovery to clinical applications, healthcare and global health that can be viewed broadly as the spectrum of work that marks the pathway from discovery to global health.