评估饲料中使用噬菌体鸡尾酒控制肉鸡鼠伤寒沙门氏菌和肠炎沙门氏菌感染的体外和体内效率。

IF 2.5 2区农林科学 Q1 VETERINARY SCIENCES

Avian Pathology Pub Date : 2024-06-01 Epub Date: 2024-01-25 DOI:10.1080/03079457.2024.2304628

Amir Hossein Pourabadeh, Seyed Ahmad Madani, Ruhollah Dorostkar, Mohammad Rezaeian, Hossein Esmaeili, Masoumeh Bolandian, Ali Salavati, Seyed Mohammad Mahdi Hashemian, Arezoo Aghahasani

引用次数: 0

摘要

应用噬菌体（BP）是控制家禽沙门氏菌病的一种可行方法。然而，野外分离物对不同噬菌体的敏感性会限制其在家禽业中的应用。在这项调查中，我们评估了 20 株野外沙门氏菌分离株（包括 10 株秋伤寒沙门氏菌和 10 株肠炎沙门氏菌）对噬菌体鸡尾酒的敏感性。在此次调查中，所研究的噬菌体鸡尾酒对所有野外分离菌都有很好的杀灭效果。在不同的 pH 值（5.5-8）和温度条件下（25℃ 和 37℃，48 小时；55℃，10 分钟），鸡尾酒噬菌体的溶菌活性都能保持不变。BP 鸡尾酒的物理化学抗性表明，它有潜力用作控制沙门氏菌污染的饲料添加剂。在被肠炎沙门氏菌和鼠伤寒沙门氏菌污染的饲料中添加 BP 鸡尾酒，可显著减少沙门氏菌在肉鸡肝脏、嗉囊、脾脏和盲肠中的定植（7、14 和 21 天）。

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Evaluation of the in vitro and in vivo efficiency of in-feed bacteriophage cocktail application to control Salmonella Typhimurium and Salmonella Enteritidis infection in broiler chicks.

Research highlights: Bacteriophage (BP) cocktail was partially resistant to different temperatures and pH values.The BP cocktail showed lytic effects on different Salmonella isolates.The BP cocktail reduced Salmonella colonization in the internal organs of broilers.

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来源期刊

Avian Pathology 农林科学-兽医学

CiteScore

4.50

自引率

10.70%

发文量

审稿时长

1 months

期刊介绍： Avian Pathology is the official journal of the World Veterinary Poultry Association and, since its first publication in 1972, has been a leading international journal for poultry disease scientists. It publishes material relevant to the entire field of infectious and non-infectious diseases of poultry and other birds. Accepted manuscripts will contribute novel data of interest to an international readership and will add significantly to knowledge and understanding of diseases, old or new. Subject areas include pathology, diagnosis, detection and characterisation of pathogens, infections of possible zoonotic importance, epidemiology, innate and immune responses, vaccines, gene sequences, genetics in relation to disease and physiological and biochemical changes in response to disease. First and subsequent reports of well-recognized diseases within a country are not acceptable unless they also include substantial new information about the disease or pathogen. Manuscripts on wild or pet birds should describe disease or pathogens in a significant number of birds, recognizing/suggesting serious potential impact on that species or that the disease or pathogen is of demonstrable relevance to poultry. Manuscripts on food-borne microorganisms acquired during or after processing, and those that catalogue the occurrence or properties of microorganisms, are unlikely to be considered for publication in the absence of data linking them to avian disease.