用分析方法评估叶枯素的植物化学成分、抗氧化剂和抗糖尿病活性

IF 0.3 Q4 PHARMACOLOGY & PHARMACY
Rohit Malhotra, Louis Cojandaraj
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引用次数: 0

摘要

Nitophyllum marginale 因其生物活性化合物而具有医疗应用潜力,使其有望开发出新的治疗干预措施。我们的研究旨在评估使用甲醇和氯仿溶剂提取的边缘叶菜提取物的生物活性。本研究的重点是分析海藻提取物的植物化学成分、抗氧化活性和抗糖尿病潜力。通过研究 Nitophyllum marginale 的药用特性,我们旨在探索其治疗生物活性潜力及其在改善和寻找治疗糖尿病的潜在替代品方面的作用。此外,还进行了α-葡萄糖苷酶抑制试验,以评估其作为抗糖尿病剂的潜力。研究表明,边茶提取物含有抗氧化剂,可保护细胞免受氧化应激。这些提取物还含有生物活性化合物,如生物碱、黄酮类、酚类、皂苷和碳水化合物。这些化合物共同发挥抗氧化作用。此外,提取物还显示出对α-葡萄糖苷酶的活性,而α-葡萄糖苷酶对控制血糖水平至关重要。这些结果表明,使用氯仿和甲醇溶剂从提取物中提取的生物活性代谢物具有植物化学、抗氧化和抗糖尿病活性。这些研究结果表明,叶绿素提取物具有作为天然抗氧化剂和抗糖尿病药物宝库的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Phytochemicals, Antioxidants, and Antidiabetic Activity of Nitophyllum marginale by Using Analytical Approaches
Nitophyllum marginale holds potential for medical applications due to its bioactive compounds, making it promising for developing new therapeutic interventions. Our study aims to evaluate the bioactivity of Nitophyllum marginale extracts obtained using methanol and chloroform solvents. We focus on analyzing the phytochemical profile, antioxidant activity, and antidiabetic potential of seaweed extract in this study. By examining the medicinal properties of Nitophyllum marginale, we aim to explore the therapeutic bioactivity potentiality and its prime role in improvising and searching for potential alternatives for seizing Diabetes mellitus. The antioxidant activity of Nitophyllum marginale was evaluated using ABTS, DPPH, nitric oxide, lipid peroxidation, and hydrogen peroxide assays. Additionally, alphaglucosidase inhibition tests were conducted to evaluate the potential as an antidiabetic agent. The study revealed that extracts from Nitophyllum marginale contain antioxidants that protect cells from oxidative stress. These extracts also contain bioactive compounds like alkaloids, flavonoids, phenols, saponins, and carbohydrates. These compounds work together to provide antioxidant benefits. Additionally, the extracts showed activity against alpha-glucosidase, which is vital for managing blood sugar levels. These results emphasize the existence of bioactive metabolites exhibiting phytochemicals, antioxidants, and antidiabetic activities obtained from the extract using chloroform and methanol solvents. These findings suggest the potential of Nitophyllum marginale extracts as a natural reservoir of antioxidants and antidiabetic agents.
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来源期刊
Current Drug Therapy
Current Drug Therapy PHARMACOLOGY & PHARMACY-
CiteScore
1.30
自引率
0.00%
发文量
50
期刊介绍: Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.
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