对可遗传基因组编辑辩论中不同 "身份 "概念的分析。

IF 2.3 2区 哲学 Q1 ETHICS
Medicine Health Care and Philosophy Pub Date : 2024-03-01 Epub Date: 2024-01-08 DOI:10.1007/s11019-023-10189-1
Ying-Qi Liaw
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引用次数: 0

摘要

人类可遗传基因组编辑(HHGE)涉及编辑人类配子和/或人类早期胚胎的基因。虽然 "身份 "是当前 HHGE 辩论的一个关键概念,但缺乏对不同 "身份 "概念的包容性分析,这使得整个辩论有时令人困惑。本文首先对现有文献进行了梳理,归纳了在关于 HHGE 的讨论中对 "身份 "的讨论。从本质上讲,讨论将揭示在涉及不同类型身份时对身份的本体论和经验论理解。在此,我将讨论遗传、数字、定性和叙事,以及每种类型如何与高等性别平等问题相关。其次,考虑到身份的不同类型,本文探讨了我们如何以一种促进主要利益相关者和公众在 HHGE 辩论中进行包容和知情讨论的方式来驾驭这些对身份的不同解释。在此,我主张并完善一个多层面的身份概念,将其作为讨论 HHGE 的伦理和社会影响的合适框架,因为它不仅可以整合对身份的不同理解,还可以强调这些不同理解之间的相互联系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An analysis of different concepts of "identity" in the heritable genome editing debate.

Human heritable genome editing (HHGE) involves editing the genes of human gametes and/or early human embryos. Whilst 'identity' is a key concept underpinning the current HHGE debate, there is a lack of inclusive analysis on different concepts of 'identity' which renders the overall debate confusing at times. This paper first contributes to reviewing the existing literature by consolidating how 'identity' has been discussed in the HHGE debate. Essentially, the discussion will reveal an ontological and empirical understanding of identity when different types of identity are involved. Here, I discuss genetic, numerical, qualitative and narrative and how each of them is relevant in the HHGE context. Secondly, given the different types of identity, the paper explores how we could navigate these different interpretations of identity in a way that promotes an inclusive and informed discussion between primary stakeholders and the general public in the HHGE debate. Here, I argue for and refine a multi-faceted concept of identity as a suitable framework for discussing the ethical and societal implications of HHGE because it not only could integrate different understandings of identity but also highlight the interconnectedness between these different understandings.

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来源期刊
CiteScore
4.30
自引率
4.80%
发文量
64
期刊介绍: Medicine, Health Care and Philosophy: A European Journal is the official journal of the European Society for Philosophy of Medicine and Health Care. It provides a forum for international exchange of research data, theories, reports and opinions in bioethics and philosophy of medicine. The journal promotes interdisciplinary studies, and stimulates philosophical analysis centered on a common object of reflection: health care, the human effort to deal with disease, illness, death as well as health, well-being and life. Particular attention is paid to developing contributions from all European countries, and to making accessible scientific work and reports on the practice of health care ethics, from all nations, cultures and language areas in Europe.
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