{"title":"氧化应激和神经退行性疾病中的抗氧化剂","authors":"Tukur Zayyanu","doi":"10.18535/jmscr/v11i8.02","DOIUrl":null,"url":null,"abstract":"Background: Natural substances have long been used for developing traditional medicines, and the production of innovative drugs is encouraged by the use of these natural ingredients. The key interaction between oxidative stress and inflammation in disease etiology is supported by mounting research. Reactive oxygen species (ROS) generated by inflammatory cells cause oxidative stress, which has been recognized as the key mediator of the relationship between inflammation and the spread for diseases. Curcumin (DFM), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC) are the three main components of the rhizomes of turmeric. That filters the superoxide radicals, nitric oxide, and hydrogen peroxide while inhibiting lipid peroxidation, a successful Nano medicine using a curcumin will result in treatment of age-related neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease. Aims: The goal of this research is to present a new current Nano biotechnological approach to disease treatment and the use of encapsulated Nano cur cumin for treatment of age-related neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases.","PeriodicalId":16362,"journal":{"name":"Journal of Medical Science And clinical Research","volume":"78 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Antioxidant in Oxidative Stress and Neurodegenerative Diseases\",\"authors\":\"Tukur Zayyanu\",\"doi\":\"10.18535/jmscr/v11i8.02\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Natural substances have long been used for developing traditional medicines, and the production of innovative drugs is encouraged by the use of these natural ingredients. The key interaction between oxidative stress and inflammation in disease etiology is supported by mounting research. Reactive oxygen species (ROS) generated by inflammatory cells cause oxidative stress, which has been recognized as the key mediator of the relationship between inflammation and the spread for diseases. Curcumin (DFM), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC) are the three main components of the rhizomes of turmeric. That filters the superoxide radicals, nitric oxide, and hydrogen peroxide while inhibiting lipid peroxidation, a successful Nano medicine using a curcumin will result in treatment of age-related neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease. Aims: The goal of this research is to present a new current Nano biotechnological approach to disease treatment and the use of encapsulated Nano cur cumin for treatment of age-related neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases.\",\"PeriodicalId\":16362,\"journal\":{\"name\":\"Journal of Medical Science And clinical Research\",\"volume\":\"78 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Science And clinical Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18535/jmscr/v11i8.02\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Science And clinical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18535/jmscr/v11i8.02","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Antioxidant in Oxidative Stress and Neurodegenerative Diseases
Background: Natural substances have long been used for developing traditional medicines, and the production of innovative drugs is encouraged by the use of these natural ingredients. The key interaction between oxidative stress and inflammation in disease etiology is supported by mounting research. Reactive oxygen species (ROS) generated by inflammatory cells cause oxidative stress, which has been recognized as the key mediator of the relationship between inflammation and the spread for diseases. Curcumin (DFM), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC) are the three main components of the rhizomes of turmeric. That filters the superoxide radicals, nitric oxide, and hydrogen peroxide while inhibiting lipid peroxidation, a successful Nano medicine using a curcumin will result in treatment of age-related neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease. Aims: The goal of this research is to present a new current Nano biotechnological approach to disease treatment and the use of encapsulated Nano cur cumin for treatment of age-related neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases.