利多卡因注射液联合或不联合曲安奈德治疗腹股沟疝成形术后慢性疼痛的作用

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摘要

背景:腹股沟疝成形术又称 Lichtenstein 修补术,是治疗腹股沟疝的常见手术,可导致慢性腹股沟疼痛。局部麻醉阻滞结合皮质类固醇(如利多卡因和曲安奈德)已被用于术后疼痛治疗。本研究旨在比较利多卡因联合曲安奈德与单用利多卡因治疗腹股沟疝成形术患者慢性疼痛的疗效。 研究方法巴基斯坦卡拉奇 Kulsoom Bai Valika 医院外科于 2022 年 6 月至 2023 年 6 月开展了一项随机对照试验研究。研究对象包括接受腹股沟疝成形术的 18 岁以上患者。第一组(75 人)使用利多卡因和曲安奈德,第二组(75 人)仅使用利多卡因。采用视觉模拟量表(VAS)对术后第一周、第一个月和第三个月的疼痛程度进行评估。 结果显示第一组第一周的疼痛发生率为 25%,明显低于第二组的 41.3%(P=0.024)。风险比(RR)为 0.65 (95% CI=0.43-0.97, p=0.037)。第 1 个月,第 1 组的疼痛发生率为 13.3%,而第 2 组为 29.3%(P=0.017),RR 为 0.56(95% CI=0.33-0.97)。同样,在第 3 个月,第 1 组的疼痛发生率为 9.3%,而第 2 组为 22.7%(P=0.026),RR 为 0.48(95% CI=0.23-0.97)。 结论利多卡因联合曲安奈德是治疗腹股沟疝成形术术后慢性疼痛的有效方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of Injection Lidocaine with and without Triamcinolone Acetonide in the Management of Chronic Pain in Post-Operative Inguinal Hernioplasty
Background: Inguinal hernioplasty, also called Lichtenstein repair, is a common surgical procedure for inguinal hernia which can lead to chronic groin pain. Local anesthetic blocks combined with corticosteroids like lidocaine and triamcinolone have been used for post-operative pain management. This study aimed to compare the efficacy of lidocaine with triamcinolone acetonide versus lidocaine alone for chronic pain management in patients who underwent inguinal hernioplasty. Methods: A randomized control trial study was conducted at the Department of Surgery, Kulsoom Bai Valika Hospital, Karachi, Pakistan, from June 2022 to June 2023. The study included patients undergoing inguinal hernioplasty who were over 18 years of age. Group 1 (n=75) received a combination of lidocaine with triamcinolone acetonide, while group 2 (n=75) received lidocaine alone. Pain levels were assessed using the visual analog scale (VAS) during 1st week, 1st month, and 3rd month after the surgery. Results: In group 1, the incidence of pain in the 1st week was 25%, significantly lower than the 41.3% in group 2 (p=0.024). The risk ratio (RR) was 0.65 (95% CI=0.43-0.97, p=0.037). In the 1st month, group 1 had a 13.3% incidence of pain compared to 29.3% in group 2 (p=0.017), with an RR of 0.56 (95% CI=0.33-0.97). Similarly, in the 3rd month, group 1 had a 9.3% incidence of pain compared to 22.7% in group 2 (p=0.026), with an RR of 0.48 (95% CI=0.23-0.97). Conclusion: Lidocaine with triamcinolone acetonide is an effective approach for managing chronic postoperative pain in inguinal hernioplasty.
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