评估慢性肾病患者足部溃疡的风险因素。

IF 1.4 4区医学 Q3 DERMATOLOGY

Wounds : a compendium of clinical research and practice Pub Date : 2023-10-01 DOI:10.25270/wnds/23053

Vacide Aşık Özdemir, Nesrin Nural

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引用次数: 0

摘要

引言与糖尿病一样，慢性肾脏病也是足部溃疡发生和发展的一个独立危险因素。目的作者研究了患有或不患有慢性肾功能衰竭（CKD）、患有或不患有慢性肾功能衰竭（DM）的患者，以及接受或不接受 HD 的患者足部溃疡的发病率和风险因素。材料和方法根据是否接受 HD 治疗，将患有或不患有 DM 的肾功能衰竭患者分为 4 组，每组 40 人。通过患者信息表、足部体格检查和风险评估表收集数据。结果下肢溃疡发生率最高的是第 3 组（HD+DM+）（15% [40 例中的 6 例]），即接受 HD 治疗的 CKD 和 DM 患者（P = .421）。与其他组别相比，第 3 组患者发生足部溃疡的风险最高（72.5%）（P = .001）。与足部溃疡相关的风险因素包括：晚期（即 4 期或 5 期）CKD、HD 治疗、年龄、体重指数、下肢溃疡和/或截肢史、足部畸形、皮肤和指甲病变、神经病变和血管功能不全。结论接受 HD 治疗的 CKD 患者发生足部溃疡的风险很高，而且这种风险会随着 DM 的存在而增加。

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Evaluation of risk factors for foot ulceration in individuals with chronic kidney disease.

INTRODUCTION CKD, like DM, is an independent risk factor for the development and course of foot ulcers. OBJECTIVE The authors studied the incidence and risk factors of foot ulceration in patients with CKD and with or without DM and in patients receiving or not receiving HD. MATERIALS AND METHODS Patients with or without DM and with renal failure were divided into 4 groups of 40 patients each according to whether or not they were receiving HD. Data were collected using a patient information form, physical examination of the foot, and risk assessment forms. RESULTS Lower extremity ulceration was highest in group 3 (HD+DM+) (15% [6 of 40]), that is, in patients with CKD and DM receiving HD (P = .421). Patients in group 3 were at highest risk for foot ulcers (72.5%) compared with other groups (P = .001). Risk factors associated with foot ulceration were advanced stage (ie, stage 4 or 5) CKD, HD treatment, age, BMI, history of lower extremity ulceration and/or amputation, foot deformities, skin and nail pathology, neuropathy, and vascular insufficiency. CONCLUSIONS Patients with CKD receiving HD are at high risk for foot ulcers, and this risk increases with the presence of DM.

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来源期刊

Wounds : a compendium of clinical research and practice 医学-皮肤病学

CiteScore

1.50

自引率

11.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Wounds is the most widely read, peer-reviewed journal focusing on wound care and wound research. The information disseminated to our readers includes valuable research and commentaries on tissue repair and regeneration, biology and biochemistry of wound healing, and clinical management of various wound etiologies. Our multidisciplinary readership consists of dermatologists, general surgeons, plastic surgeons, vascular surgeons, internal medicine/family practitioners, podiatrists, gerontologists, researchers in industry or academia (PhDs), orthopedic surgeons, infectious disease physicians, nurse practitioners, and physician assistants. These practitioners must be well equipped to deal with a myriad of chronic wound conditions affecting their patients including vascular disease, diabetes, obesity, dermatological disorders, and more. Whether dealing with a traumatic wound, a surgical or non-skin wound, a burn injury, or a diabetic foot ulcer, wound care professionals turn to Wounds for the latest in research and practice in this ever-growing field of medicine.