PREVALENCE OF INAPPROPRIATE LEFT VENTRICULAR MASS IN PATIENTS WITH VARIOUS DISEASES

Abstract. Introduction. According to the inappropriate left ventricular mass concept proposed by G. de Simone et al. (1998), in some cases, an increment in the left ventricular myocardium mass occurs inadequately to the hemodynamic load of high blood pressure. Studying the prevalence and interrelation of disproportionately high left ventricular myocardia ВЕСТНИК СОВРЕМЕННОЙ КЛИНИЧЕСКОЙ МЕДИЦИНЫ 2023 Том 16, вып. 6 131ОБЗОРЫ mass continues to remain topical to the present, due to the increased risk of cardiovascular events among affected people, and at the same time independently of the presence of left ventricular hypertrophy. Aim. To analyze the scientific medical literature data obtained in studying the prevalence of disproportionately high left ventricular myocardial mass in patients with different diseases. Materials and Methods. We reviewed and analyzed the scientific results from national and foreign medical literature in electronic databases PubMed, Medline, and eLibrary over the years 1998- 2023. Results and Discussion. Research papers dealing with studying the prevalence of disproportionately high left ventricular myocardial mass mainly present patients with cardiovascular diseases. Prevalence of disproportionately high left ventricular myocardial mass in patients with arterial hypertension varies quite widely, from 9% to 82,4%; at the same time, gender and racial differences were found. It is also common in patients with coronary heart disease, aortic stenosis, chronic kidney disease, rheumatoid arthritis, type 2 diabetes mellitus, and primary aldosteronism. It turned out that the frequency of abnormally high left ventricular myocardial mass tends to increase in cases with a combination of chronic kidney disease and type 2 diabetes mellitus. Conclusions. To thoroughly study how disproportionately high left ventricular myocardial mass contributes to bad cardiovascular prognosis, further research is needed in this theme, including studying its prevalence in patients with different diseases, both isolated and combined.