使用波长为 311 纳米的窄波段光疗法治疗副银屑病患者

T. Lytynska, S.M. Razdaibiedin, S.V. Ivanov
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摘要

副银屑病是一类异质性慢性皮肤病,其临床表现为炎性斑点和/或丘疹和斑块,表面覆盖有小片状鳞屑。副银屑病之所以具有现实意义、医学和社会重要性,不仅是因为这种病症的患者人数持续增加,而且还因为该病的临床表现多种多样、严重的侵袭性病程增加、诊断错误以及缺乏有效的治疗方法。 目的--研究波长为 311 纳米的窄带光疗在治疗副银屑病患者中的有效性和安全性。 材料和方法。对16名副银屑病患者进行了检查和治疗,其中4人(25%)被诊断为大斑块型副银屑病,4人(25%)被诊断为小斑块型副银屑病,5人(31.25%)被诊断为慢性苔癣型副银屑病,3人(18.75%)被诊断为苔癣型和脓疱型急性副银屑病。患者的年龄从 19 岁到 53 岁不等,其中女性 5 人(占 31.25%),男性 11 人(占 68.75%),病程从 6 个月到 5 年不等。治疗方法是使用 Dermalight 3000 光疗设备(德国 Dr. K. Hönle Medizintechnik GmbH)对患者进行波长为 311 nm 的窄波段光疗。 结果与讨论。治疗效果根据客观临床表现和主观体征的动态和消除程度,以及治疗的长期效果和缓解的稳定性进行评估。在疗程结束时,12 名患者(75%)的临床症状得到了恢复,4 名患者(25%)的症状得到了明显改善。所有患者在接受治疗时均未出现并发症、副作用和不良反应。 结论波长为 311 纳米的窄带光疗是治疗副银屑病患者的一种有效而安全的方法。住院病人和门诊病人均可使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The use of narrow-band phototherapy with a wavelength of 311 nm in the treatment of patients with parapsoriasis
Parapsoriasis is a heterogeneous group of chronic skin diseases, the clinical manifestations of which are inflammatory spots and/or papules and plaques covered with small lamellar scales. The relevance and medical and social importance of parapsoriasis is due not only to the permanent increase in the number of patients with this pathology, but also to the variety of clinical manifestations of the disease, the increase in severe aggressive course, errors in diagnosis and the lack of effective treatment methods. Objective — to study the effectiveness and safety of narrow-band phototherapy with a wavelength of 311 nm in the treatment of patients with parapsoriasis. Materials and methods. 16 patients with parapsoriasis were examined and treated, among whom large plaque was diagnosed in 4 (25 %), small plaque in 4 (25 %), lichenoid chronic in 5 (31.25 %), lichenoid and pustular acute parapsoriasis in 3 (18.75 %) patients. The age of the patients ranged from 19 to 53 years, there were 5 women (31.25 %), 11 men (68.75 %), the duration of the disease was from 6 months to 5 years. The treatment involved the appointment of patients with narrow-band phototherapy with a wavelength of 311 nm using the Dermalight 3000 phototherapy device (Dr. K. Hönle Medizintechnik GmbH, Germany). Results and discussion. The therapeutic effectiveness of the treatment was evaluated by the dynamics and degree of elimination of objective clinical manifestations and subjective signs of the disease, as well as by the long-term results of the treatment and the stability of remission. At the end of the course of treatment, clinical recovery was observed in 12 (75 %) patients, significant improvement in — 4 (25 %) patients. All patients underwent treatment without complications, side reactions and unwanted effects were not registered. Conclusions. Narrowband phototherapy with a wavelength of 311 nm is an effective and safe method of treating patients with parapsoriasis. Its use is possible both in inpatient and outpatient settings.
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