{"title":"病例报告:皮肤钙化症","authors":"Abhishek Jain","doi":"10.36106/paripex/6000440","DOIUrl":null,"url":null,"abstract":"Introduction: An 11 year old boy presented in the out-patient department with the chief complaints of swelling over his Right forearm and inability to completely supinate the forearm since 2 years. Additionally, he complained of blisters over his back which falls of without itching. He had no history of fever with chills/rigor, blurring of vision, fits - convulsions or any other neurosensory deficit. Patient is able to flex and extend his elbow and wrist completely b Examination: ut there is restricted supination and pronation with 30 degrees range of movement in either direction. Multiple nodules can be felt over the forearm and wrist which are tender on palpation. Nodules are hard, slightly mobile with movement of the wrist and forearm. Hard white blisters present on the extensor areas of arm and back. Radiologicall Approach: y, on X-ray multiple calcified circular lesions (target sign) present in multiple planes in different sizes in between the ulna and radius. There is bowing of the forearm bones with disrupted inferior radio-ulna joint. On MRI, calcified lesions are confirmed lying within the subcutaneous planes, muscular compartments and also involving the intramuscular septum. Blood reports showed eosinophilia(7.45%) with Erythrocyte Sedimentation Rate 18mm/hr and C-Reactive Proteins 1mg/dl. On HPE, section study showed fibro-collagenous tissue showing marked areas of calcification with surrounding dense fibrosis suggestive of Calcinosis Cutis. Initially, patient was managed for skeletal cysticer Discussion: cosis with albendazole but with negative ELISA and normal CT head, en-masse dissection of one lesion from dorsum of wrist was done under fluoroscopy and sent for Histo-pathological Examination. Calcinosis cutis is a rare condition which we discovered in this patient.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"29 10","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"CASE REPORT: CALCINOSIS CUTIS\",\"authors\":\"Abhishek Jain\",\"doi\":\"10.36106/paripex/6000440\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: An 11 year old boy presented in the out-patient department with the chief complaints of swelling over his Right forearm and inability to completely supinate the forearm since 2 years. Additionally, he complained of blisters over his back which falls of without itching. He had no history of fever with chills/rigor, blurring of vision, fits - convulsions or any other neurosensory deficit. Patient is able to flex and extend his elbow and wrist completely b Examination: ut there is restricted supination and pronation with 30 degrees range of movement in either direction. Multiple nodules can be felt over the forearm and wrist which are tender on palpation. Nodules are hard, slightly mobile with movement of the wrist and forearm. Hard white blisters present on the extensor areas of arm and back. Radiologicall Approach: y, on X-ray multiple calcified circular lesions (target sign) present in multiple planes in different sizes in between the ulna and radius. There is bowing of the forearm bones with disrupted inferior radio-ulna joint. On MRI, calcified lesions are confirmed lying within the subcutaneous planes, muscular compartments and also involving the intramuscular septum. Blood reports showed eosinophilia(7.45%) with Erythrocyte Sedimentation Rate 18mm/hr and C-Reactive Proteins 1mg/dl. On HPE, section study showed fibro-collagenous tissue showing marked areas of calcification with surrounding dense fibrosis suggestive of Calcinosis Cutis. Initially, patient was managed for skeletal cysticer Discussion: cosis with albendazole but with negative ELISA and normal CT head, en-masse dissection of one lesion from dorsum of wrist was done under fluoroscopy and sent for Histo-pathological Examination. Calcinosis cutis is a rare condition which we discovered in this patient.\",\"PeriodicalId\":19910,\"journal\":{\"name\":\"Paripex Indian Journal Of Research\",\"volume\":\"29 10\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Paripex Indian Journal Of Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36106/paripex/6000440\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Paripex Indian Journal Of Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36106/paripex/6000440","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
简介:门诊部接诊了一名 11 岁男孩,主诉是右前臂肿胀,两年来一直无法完全上举。此外,他还诉说背部出现水泡,水泡脱落后没有瘙痒感。他没有发热伴寒战/发冷、视力模糊、抽搐或任何其他神经感觉障碍的病史。患者的肘部和腕部能够完全弯曲和伸展 b 检查:患者的上举和前倾均受限,两个方向的活动范围均为 30 度。前臂和腕部可摸到多个结节,触诊时有压痛。结节较硬,随着手腕和前臂的活动而轻微移动。手臂和背部的伸展部位出现硬的白色水泡。放射学方法:在 X 光片上,尺骨和桡骨之间的多个平面上出现大小不等的多个钙化圆形病灶(靶征)。前臂骨骼呈弓形,下尺桡关节紊乱。核磁共振检查证实,钙化病灶位于皮下平面、肌肉区,还累及肌内隔膜。血液报告显示嗜酸性粒细胞增多(7.45%),红细胞沉降率为18毫米/小时,C反应蛋白为1毫克/分升。HPE切片显示纤维胶原组织有明显的钙化区域,周围有致密的纤维化,提示为皮肤钙化症。最初,患者因骨骼囊肿病接受了阿苯达唑治疗,但 ELISA 阴性,头颅 CT 正常,于是在透视下从手腕背侧切除了一个病灶,并送去做组织病理学检查。我们在这名患者身上发现的皮肤钙化症是一种罕见病。
Introduction: An 11 year old boy presented in the out-patient department with the chief complaints of swelling over his Right forearm and inability to completely supinate the forearm since 2 years. Additionally, he complained of blisters over his back which falls of without itching. He had no history of fever with chills/rigor, blurring of vision, fits - convulsions or any other neurosensory deficit. Patient is able to flex and extend his elbow and wrist completely b Examination: ut there is restricted supination and pronation with 30 degrees range of movement in either direction. Multiple nodules can be felt over the forearm and wrist which are tender on palpation. Nodules are hard, slightly mobile with movement of the wrist and forearm. Hard white blisters present on the extensor areas of arm and back. Radiologicall Approach: y, on X-ray multiple calcified circular lesions (target sign) present in multiple planes in different sizes in between the ulna and radius. There is bowing of the forearm bones with disrupted inferior radio-ulna joint. On MRI, calcified lesions are confirmed lying within the subcutaneous planes, muscular compartments and also involving the intramuscular septum. Blood reports showed eosinophilia(7.45%) with Erythrocyte Sedimentation Rate 18mm/hr and C-Reactive Proteins 1mg/dl. On HPE, section study showed fibro-collagenous tissue showing marked areas of calcification with surrounding dense fibrosis suggestive of Calcinosis Cutis. Initially, patient was managed for skeletal cysticer Discussion: cosis with albendazole but with negative ELISA and normal CT head, en-masse dissection of one lesion from dorsum of wrist was done under fluoroscopy and sent for Histo-pathological Examination. Calcinosis cutis is a rare condition which we discovered in this patient.