K. Titov, E. V. Shutov, A. A. Alimov, S. S. Lebedev, A. Kirichek, G. M. Zapirov
{"title":"转移性肾癌联合药物治疗的肾毒性","authors":"K. Titov, E. V. Shutov, A. A. Alimov, S. S. Lebedev, A. Kirichek, G. M. Zapirov","doi":"10.17650/1726-9776-2023-19-3-153-162","DOIUrl":null,"url":null,"abstract":"The review covers reduced kidney function in the context of renal cell carcinoma. According to international studies, some patients already have chronic kidney disease at time of disease onset. Surgical treatment leads to a decrease in the total number of functioning nephrons. Drug therapy causes several adverse events including nephrotoxicity. The review discusses the problem of using combination regimens in patients with solitary kidney.","PeriodicalId":216890,"journal":{"name":"Cancer Urology","volume":"27 6","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nephrotoxicity of combination drug therapy in metastatic renal cancer\",\"authors\":\"K. Titov, E. V. Shutov, A. A. Alimov, S. S. Lebedev, A. Kirichek, G. M. Zapirov\",\"doi\":\"10.17650/1726-9776-2023-19-3-153-162\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The review covers reduced kidney function in the context of renal cell carcinoma. According to international studies, some patients already have chronic kidney disease at time of disease onset. Surgical treatment leads to a decrease in the total number of functioning nephrons. Drug therapy causes several adverse events including nephrotoxicity. The review discusses the problem of using combination regimens in patients with solitary kidney.\",\"PeriodicalId\":216890,\"journal\":{\"name\":\"Cancer Urology\",\"volume\":\"27 6\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cancer Urology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17650/1726-9776-2023-19-3-153-162\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer Urology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17650/1726-9776-2023-19-3-153-162","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nephrotoxicity of combination drug therapy in metastatic renal cancer
The review covers reduced kidney function in the context of renal cell carcinoma. According to international studies, some patients already have chronic kidney disease at time of disease onset. Surgical treatment leads to a decrease in the total number of functioning nephrons. Drug therapy causes several adverse events including nephrotoxicity. The review discusses the problem of using combination regimens in patients with solitary kidney.