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引用次数: 0
摘要
有机磷化合物被用作商业杀虫剂,以气溶胶或粉尘的形式施用。有意或无意地摄入这些化合物会导致危险状况,甚至致命。治疗有机磷中毒最常见的障碍是在农村地区缺乏足够的医疗服务和设备来提供适当的急救服务,因为在农村地区,重症监护和急症监护之间存在很大的差距。阿托品是有机磷中毒的解毒剂。阿托品的剂量主要取决于有机磷的中毒剂量。阿托品是毒蕈碱突触后膜上乙酰胆碱的竞争性拮抗剂。阿托品能阻断体内所有毒蕈碱作用。作者介绍了一例 OP 中毒自杀病例,并概述了急性中毒的处理方法。早期识别症状和及时治疗有助于降低发病率和死亡率。
A Case Study on Organophosphate Poisoning in Dehradun
Organophosphate compounds are used as commercial insecticides and applied as aerosols or dust. Consuming these compounds intentionally or unintentionally lead to dangerous conditions even to fatality. The most common obstacle in treating organophosphorus poisoning is the availability of sufficient medical care, equipment to provide proper emergency care observed in rural areas where there is a lot of gaps between intensive care and acute care. Atropine use is as an antidote in organophosphorus poisoning. The dose of atropine mainly depends on the organophosphorus toxic doses. Atropine is a competitive antagonist of acetylcholine at the muscarinic postsynaptic membrane. Atropine blocks all the muscarinic effects in the body. The authors present a case of suicidal OP poisoning with an overview of management of the acute intoxication. The early recognition of symptoms and prompt treatment helps in reducing the morbidity and mortality.