{"title":"人型心脏杆菌引起的腰椎骨髓炎和硬膜外脓肿--儿科首例报告病例:通用 16S rRNA 基因 PCR 和测序的作用","authors":"Moamen Al Zoubi, Huma M. Khan, Sona Najafi","doi":"10.1097/ipc.0000000000001329","DOIUrl":null,"url":null,"abstract":"This report presents a case of a 14-year-old female patient diagnosed with lumbar (L2–L3) epidural abscess and vertebral osteomyelitis caused by Cardiobacterium hominis. The diagnosis was made using universal 16S rRNA polymerase chain reaction. To the best of our knowledge, this is the first reported case of C. hominis lumbar epidural abscess and vertebral osteomyelitis in pediatric population. This case serves to illustrate the potential value of polymerase chain reaction and DNA sequencing in diagnosing culture-negative vertebral osteomyelitis and the potential role of C. hominis in causing this infection.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Lumbar Osteomyelitis and Epidural Abscess Caused by Cardiobacterium hominis—First Reported Case in the Pediatric Population: The Role of Universal 16S rRNA Gene PCR and Sequencing\",\"authors\":\"Moamen Al Zoubi, Huma M. Khan, Sona Najafi\",\"doi\":\"10.1097/ipc.0000000000001329\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This report presents a case of a 14-year-old female patient diagnosed with lumbar (L2–L3) epidural abscess and vertebral osteomyelitis caused by Cardiobacterium hominis. The diagnosis was made using universal 16S rRNA polymerase chain reaction. To the best of our knowledge, this is the first reported case of C. hominis lumbar epidural abscess and vertebral osteomyelitis in pediatric population. This case serves to illustrate the potential value of polymerase chain reaction and DNA sequencing in diagnosing culture-negative vertebral osteomyelitis and the potential role of C. hominis in causing this infection.\",\"PeriodicalId\":13952,\"journal\":{\"name\":\"Infectious Diseases in Clinical Practice\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2023-11-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Infectious Diseases in Clinical Practice\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/ipc.0000000000001329\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infectious Diseases in Clinical Practice","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/ipc.0000000000001329","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
摘要
本报告介绍了一例 14 岁女性患者的病例,她被诊断为腰椎(L2-L3)硬膜外脓肿和脊椎骨髓炎,病因是人类心脏杆菌(Cardiobacterium hominis)。诊断是通过通用 16S rRNA 聚合酶链反应做出的。据我们所知,这是首例报道的儿童腰椎硬膜外脓肿和椎体骨髓炎病例。该病例说明了聚合酶链式反应和 DNA 测序在诊断培养阴性的脊椎骨髓炎中的潜在价值,以及人尾蚴在导致这种感染中的潜在作用。
Lumbar Osteomyelitis and Epidural Abscess Caused by Cardiobacterium hominis—First Reported Case in the Pediatric Population: The Role of Universal 16S rRNA Gene PCR and Sequencing
This report presents a case of a 14-year-old female patient diagnosed with lumbar (L2–L3) epidural abscess and vertebral osteomyelitis caused by Cardiobacterium hominis. The diagnosis was made using universal 16S rRNA polymerase chain reaction. To the best of our knowledge, this is the first reported case of C. hominis lumbar epidural abscess and vertebral osteomyelitis in pediatric population. This case serves to illustrate the potential value of polymerase chain reaction and DNA sequencing in diagnosing culture-negative vertebral osteomyelitis and the potential role of C. hominis in causing this infection.
期刊介绍:
Medical professionals seeking an infectious diseases journal with true clinical value need look no further than Infectious Diseases in Clinical Practice. Here, clinicians can get full coverage consolidated into one resource, with pertinent new developments presented in a way that makes them easy to apply to patient care. From HIV care delivery to Hepatitis C virus testing…travel and tropical medicine…and infection surveillance, prevention, and control, Infectious Diseases in Clinical Practice delivers the vital information needed to optimally prevent and treat infectious diseases. Indexed/abstracted in: EMBASE, SCOPUS, Current Contents/Clinical Medicine