COVID-19 大流行对骨科择期手术和机构骨库活动的不利影响

S. Zeljko, Ristic M. Branko, Matic V Aleksandar
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引用次数: 0

摘要

摘要 新型冠状病毒 SARS-CoV-2(COVID-19)引发了 2020 年的全球大流行,对世界经济和医疗保健系统造成了严重影响。本文旨在描述 COVID-19 大流行对大学医院选择性关节置换手术和骨库活动的影响。我们进行了一项回顾性队列研究,涉及 600 名成年骨科住院患者,时间分别为 2019 年 3 月 15 日至 2020 年 12 月 31 日。初次全髋关节和膝关节置换术的数量出现了非常显著的下降,分别从 2019 年同期的 315 例和 165 例降至 2020 年的 106 例和 14 例(P < 0.001)。与2019年同期相比,大流行期间的采购程序总数出现了非常明显的下降(p < 0.001)。在COVID-19大流行期间,骨异体移植物的总体废弃率从31.57%大幅上升至80.76%(p < 0.03)。在2019年和2020年期间,造成异体移植物排斥的主要原因是由于缺乏机构支持或捐赠者拒绝进行为期6个月的复检而无法进行血清学检测。COVID-19大流行对骨科择期手术和机构骨库的正常运作造成了极为不利的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Detrimental Effects of the COVID-19 Pandemic on Elective Orthopedic Surgery and Institutional Bone Bank Activity
Abstract The novel coronavirus SARS-CoV-2 (COVID-19) generated a 2020 global pandemic that has provoked drastic effects across world economies and healthcare systems. This article aimed to describe the impact of the COVID-19 pandemic on elective arthroplasty procedures and bone bank activity in the university hospital. We have performed a retrospective cohort study involving 600 adult orthopedic inpatients from March 15th to December 31st, 2019 and 2020, respectively. The number of primary total hip and knee arthroplasty procedures showed a highly significant decrease from 315 and 165 in the same period of 2019 to 106 and 14 in 2020 (p < 0.001). There was a highly significant decrease in the overall number of procurement procedures during the pandemic compared to the same period in 2019 (p < 0.001). The overall discard rate of bone allografts during the COVID-19 pandemic significantly increased from 31.57%. to 80.76% (p < 0.03). The leading cause of allograft rejection during 2019 and 2020 was the inability to perform serological tests due to lack of institutional support or the refusal of donors to perform a six-month retest. The COVID-19 pandemic had an extremely detrimental effect on elective orthopedic surgery and the normal functioning of the institutional bone bank.
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