睾丸假体并发症:原因分析、手术策略、预防方法

I. Shormanov, D. N. Shchedrov, Y. S. Spasskaya, D. Garova
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The results of testicular prosthetics were analyzed in 292 patients aged 12–59 years in the period 2007–2022. Various complications were found in 27 patients (9.24 %), including in the adolescent group (12–17 years) – in 13 (8.33 %) patients out of 156, in adults – in 14 (10.29 %) out of 136. MIT implants were used in 116 cases (adults – 54, adolescents – 62) and Promedon implants – in 176 cases (adults – 80, adolescents – 96). Data processing was carried out in the Statistica 20.0 program. The p <0.05 level was considered statistically significant.Results. The most common complications include implant extrusion (22.2 %) and surgical hemostasis disorders (29.6 %), they are also the most difficult to correct and often lead to the need to remove the implant. 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引用次数: 0

摘要

背景。睾丸假体置换术的操作技术看似简单,但往往会引发并发症。同时,不同作者关于并发症发生频率和结构的数据差异极大。同时,作者们指出的导致并发症的因素往往相互矛盾,而且通常都没有进行分析,因此,预防方法和治疗策略至今都没有明确的定义。分析 18 岁以上患者和青少年儿童在睾丸修复术中出现并发症的频率和结构,并提出预防已发现并发症的最佳方法。对 2007-2022 年间 292 名 12-59 岁患者的睾丸修复术结果进行了分析。发现27名患者(9.24%)出现了各种并发症,其中青少年组(12-17岁)156人中有13人(8.33%)出现并发症,成人组136人中有14人(10.29%)出现并发症。使用 MIT 种植体的有 116 例(成人 54 例,青少年 62 例),使用 Promedon 种植体的有 176 例(成人 80 例,青少年 96 例)。数据处理在 Statistica 20.0 程序中进行。P<0.05为具有统计学意义。最常见的并发症包括种植体挤出(22.2%)和手术止血障碍(29.6%),这两种并发症也是最难纠正的并发症,往往需要将种植体取出。在手术过程中使用抗菌治疗并不能降低并发症的风险,如果不使用抗生素预防,并发症的发生率在成人组会增加 3.9%,在青少年组会增加 2.28%。最合理的单一围手术期抗生素预防。使用 MIT 种植体时的并发症发生率(n = 17)高于 Promedon(n = 10)。在原发性睾丸切除术后三年以上或最初阴囊发育不良的患者组中,并发症的发生率明显更高。睾丸假体的并发症发生率为 8.33-10.29%。睾丸假体并发症的结构以止血和假体挤出并发症为主,这些并发症也是造成重复干预次数最多的原因,也是取出假体的原因。影响并发症形成的因素有很多--入路、抗菌治疗/预防方案、植入材料、初次手术后的时间。最合理的方法是在筋膜上入路的睾丸切除术后 6-12 个月使用现代硅胶假体,并在围手术期使用一次抗生素预防。通过采取预防措施,可以降低最危险和最常见并发症的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Complications of testicular prosthetics: analysis of causes, surgical tactics, ways of prevention
Background. Testicular prosthetics, despite the apparent simplicity of the technique of performing the operation, often leads to complications. At the same time, the spread of data from different authors on the frequency and structure of complications is extremely large. At the same time, the factors indicated by the authors as the causes of complications often contradict each other, and, as a rule, are not analyzed, therefore, methods of prevention and therapeutic tactics are not clearly defined today.Aim. To analyze the frequency and structure of complications during testicular prosthetics in patients over 18 years of age and adolescent children, as well as to suggest optimal ways to prevent the identified complications.Materials and methods. The results of testicular prosthetics were analyzed in 292 patients aged 12–59 years in the period 2007–2022. Various complications were found in 27 patients (9.24 %), including in the adolescent group (12–17 years) – in 13 (8.33 %) patients out of 156, in adults – in 14 (10.29 %) out of 136. MIT implants were used in 116 cases (adults – 54, adolescents – 62) and Promedon implants – in 176 cases (adults – 80, adolescents – 96). Data processing was carried out in the Statistica 20.0 program. The p <0.05 level was considered statistically significant.Results. The most common complications include implant extrusion (22.2 %) and surgical hemostasis disorders (29.6 %), they are also the most difficult to correct and often lead to the need to remove the implant. The use of antibacterial therapy by the course does not reduce the risk of complications, the absence of antibiotic prophylaxis increases the incidence of complications by 3.9 % in the adult group and by 2.28 % in the adolescent group. The most rational single perioperative antibiotic prophylaxis. The frequency of complications when using MIT implants is higher (n = 17) than Promedon (n = 10). The incidence of complications is significantly higher in the group of patients who underwent prosthetics for more than three years after primary orchectomy or in an initially hypoplasized scrotum.Conclusion. Complications of testicular prosthetics are 8.33–10.29 %. The structure is dominated by complications of hemostasis and implant extrusion, they are also the cause of the greatest number of repeated interventions and the reason for the removal of the implant. A number of factors influence the formation of complications – access, the scheme of antibacterial therapy/prevention, the implantable material, the period after the initial operation. The most rational is the use of a modern silicone implant for prosthetics 6–12 months after orchectomy with suprascrotal access with a single perioperative antibiotic prophylaxis. The risk of the most dangerous and frequent complications can be leveled by using preventive measures.
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