占碑市 UPTD Puskesmas Putri Ayu 艾滋病患者淋巴细胞总数与病毒负荷检查结果之间的关系

Yeni Liyestiyana, Chas Dinda, RD Mustopa, Asnailly Asnailly
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摘要

背景:人类免疫缺陷病毒(HIV)感染会破坏人体的免疫系统,导致艾滋病(获得性免疫缺陷综合症)。淋巴细胞总数是评估 HIV 感染者细胞免疫反应的初步筛选参数之一。淋巴细胞总数减少的原因之一是服用抗逆转录病毒药物(ARVs)的影响:研究设计为横断面定量研究。本研究使用了 39 份在 Putri Ayu 健康中心接受抗逆转录病毒疗法超过 6 个月的艾滋病患者的淋巴细胞总数和病毒载量样本。研究人员根据纳入和排除标准筛选出艾滋病患者,然后通过卡方检验对数据进行单变量和双变量分析。 结果大多数受访者的淋巴细胞总数正常,有 26 人(66.7%);大多数受访者的病毒载量检测不到,有 26 人(66.7%)。根据统计检测结果,P 值为 0.000(P,<0.005)。这些结果表明,淋巴细胞总数与病毒载量检查结果之间存在显著关系。 结论:在 Putri Ayu 健康中心接受抗逆转录病毒治疗的艾滋病患者的淋巴细胞总数与病毒载量之间存在关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Relationship Between Total Lymphocyte Count and Viral Load Examination Results in HIV on Arv Patients at UPTD Puskesmas Putri Ayu Jambi City
Background: Human Immunodeficiency Virus (HIV) infection causes destruction of the body's immune system in humans, causing AIDS (Acquired Immunodeficiency Syndrome). The total number of lymphocytes is one of the parameters used as an initial screening to assess the cellular immune response in people with HIV. One of the causes of the decrease in the total number of lymphocytes is the presence of the effect of taking antiretrovirals (ARVs) Method: The research design is quantitative research with a cross sectional approach. The data in this study used 39 samples of HIV patients who received ARV therapy for more than 6 months in the form of the total number of lymphocytes and viral load at the Putri Ayu Health Center. Patients with HIV were selected according to inclusion and exclusion criteria and then the data were analyzed univariately and bivariately with chi-square tests. Result: Most respondents had a normal total lymphocyte count of 26 people (66.7%) and most respondents had an undetectable viral load of 26 people (66.7%). Based on the Statistical Test Results, a p-value of 0.000 (p, <0.005) was obtained. These results show that there is a significant relationship between the total lymphocyte count and the results of viral load examination. Conclusion: there is a relationship between the total number of lymphocytes and viral load in HIV patients who received ARV therapy at Putri Ayu Health Center.
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