占碑省 Baiturahim 医院慢性肾病不同阶段的血尿素氮与肌酸酐(BUN/CR)比率分析

Joliansyah Joliansyah, Rafael Nugra Heny, Nasrazuhdy Nasrazuhdy, James P Simanjuntak
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摘要

背景:肾功能衰竭是指肾脏功能减退直至完全无法过滤体内电解质、维持体液和体内化学物质(如血液中的钠、钾等)平衡或产生尿液的一种疾病。肾功能减退会导致血液中肌酐和尿素水平升高。肾小球滤过率或肾脏过滤血液的能力可通过测量血清肌酐水平和血尿素氮水平来评估。血清尿素氮(BUN)水平与 GFR 成反比。正常的 BUN/肌酐比率为 10-15:1。本研究旨在确定接受常规血液透析的慢性肾衰竭患者和 V 期肾衰竭患者的平均血尿素氮/肌酐比值的差异。 研究方法本研究是一项定量描述性研究,通过对 2022 年 2 月至 2023 年 2 月期间在占碑拜图拉欣医院接受治疗的 70 名患者的病历数据进行二次分析。本研究评估的变量包括肾衰竭的严重程度以及尿素和肌酐的检查结果。 研究结果研究发现,非终末期肾功能衰竭患者的平均尿素氮/肌酐比值为 11.97,而 ESRD 患者的平均尿素氮/肌酐比值为 5.69。 结论在占碑拜图拉欣医院,慢性肾衰竭和 ESRD 患者的血清白蛋白/肌酐比值结果存在明显差异(P 值 < 0.01)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of Blood Urea-Nitrogen to Creatainine (BUN/CR) Ratio at Different Stages of Chronic Kidney Disease in Baiturahim Hospital Jambi
Background: Renal failure is a disease in which the function of the kidneys decreases until they are no longer able to work at all in terms of filtering the body's electrolyte disposal, maintaining the balance of fluids and body chemicals such as sodium and potassium in the blood or urine production. Decreased kidney function indicates an increase in creatinine and urea levels in the blood. GFR or the ability of the kidneys to filter blood can be assessed by measuring serum creatinine levels, blood urea nitrogen levels. Serum blood urea nitrogen (BUN) levels are inversely proportional to GFR. The normal BUN/Creatinine ratio is 10-15:1. The aim of this study was to determine the difference in the average BUN/Creatinine ratio in patients with Chronic Kidney Failure and Stage V Kidney Failure patients undergoing routine hemodialysis. Method: This research is a quantitative descriptive study by taking secondary data from medical record data on 70 patients treated at Baiturrahim Hospital Jambi for the period February 2022-February 2023. Variables assessed in this study include the severity of kidney failure with the results of urea and creatinine examinations. Result: Based on research that has been carried out found that the average BUN/Creatinine ratio in patients at non-end stage of CKD was 11.97, while in ESRD patients it was 5.69. Conclusion: There was a significant difference between the results of the BUN/Creatinine ratio in patients with Chronic Kidney Failure and ESRD (P-value < 0.01) at Baiturrahim Hospital Jambi.
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