长 COVID 并发体位性正位性心动过速综合征的治疗--病例系列研究

IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL
Tomoya Tsuchida MD, PhD, Yuki Ishibashi MD, PhD, Yoko Inoue MD, Kosuke Ishizuka MD, PhD, Kohta Katayama MD, PhD, Masanori Hirose MD, PhD, Yu Nakagama MD, PhD, Yasutoshi Kido MD, PhD, Yoshihiro Akashi MD, PhD, Takehito Otsubo MD, PhD, Takahide Matsuda MD, PhD, Yoshiyuki Ohira MD, PhD
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引用次数: 0

摘要

冠状病毒病 2019(COVID-19)后遗症又称长COVID,可表现出各种症状。在这些症状中,自律神经失调,尤其是体位性正位性心动过速综合征(POTS),应予以评估。然而,以往缺乏关于治疗 COVID-19 并发的 POTS 的研究。因此,本研究旨在调查长 COVID 并发 POTS 的治疗过程。我们评估了首次和最后一次就诊时的治疗天数、方法和疲劳评分的变化、Schellong 试验心率的变化以及社会状况。32 名长 COVID 并发 POTS 患者接受了随访(16 名男性;中位年龄:28 岁)。随访时间为 159 天,COVID-19 发病与首次就诊之间的间隔时间为 97 天。一些患者对β受体阻滞剂治疗有反应。许多患者出现了精神症状,需要进行精神干预和服用选择性血清素再摄取抑制剂。从首次就诊到最后一次就诊,患者的心率、表现状况和就业/教育状况都有所改善。我们的研究表明,94% 的 POTS 并发长 COVID 患者的病情将在 159 天内得到改善。因此,当长COVID患者抱怨疲劳时,应考虑对POTS进行评估,并关注心理症状和社会环境。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Treatment of long COVID complicated by postural orthostatic tachycardia syndrome—Case series research

Treatment of long COVID complicated by postural orthostatic tachycardia syndrome—Case series research

Background

Coronavirus disease 2019 (COVID-19) sequelae, also known as long COVID, can present with various symptoms. Among these symptoms, autonomic dysregulation, particularly postural orthostatic tachycardia syndrome (POTS), should be evaluated. However, previous studies on the treatment of POTS complicated by COVID-19 are lacking. Therefore, this study aimed to investigate the treatment course of long COVID complicated by POTS.

Methods

The medical records of patients who complained of fatigue and met the criteria for POTS diagnosis were reviewed. We evaluated the treatment days, methods and changes in fatigue score, changes in heart rate on the Schellong test, and social situation at the first and last visits.

Results

Thirty-two patients with long COVID complicated by POTS were followed up (16 males; median age: 28 years). The follow-up period was 159 days, and the interval between COVID-19 onset and initial hospital attendance was 97 days. Some patients responded to β-blocker therapy. Many patients had psychiatric symptoms that required psychiatric intervention and selective serotonin reuptake inhibitor prescription. Changes in heart rate, performance status, and employment/education status improved from the first to the last visit. These outcomes were believed to be because of the effects of various treatment interventions and spontaneous improvements.

Conclusions

Our study suggests that the condition of 94% of patients with POTS complicated by long COVID will improve within 159 days. Therefore, POTS evaluation should be considered when patients with long COVID complain of fatigue, and attention should be paid to psychological symptoms and the social context.

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来源期刊
Journal of General and Family Medicine
Journal of General and Family Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
2.10
自引率
6.20%
发文量
79
审稿时长
48 weeks
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