将 Lobelia inflata L.作为治疗 Covid-19 引起的呼吸系统问题的替代药物:综述

Salama M. El-Darier, Habiba A. El-Zohary, Zeinab A. Farghly, Yara E. Wahba, Roufaida M. Elghobashy
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摘要

Lobelia inflata(印度烟草,凌霄花科)是一种草药,可用于治疗多种呼吸道疾病,如哮喘、支气管炎、肺炎和咳嗽。本综述的主要目的是记录 L. inflata 作为呼吸兴奋剂对 Covid-19 感染患者的潜在用途。美洲原住民将这种植物作为治疗哮喘的药物进行熏制,如今,人们有时会建议用小叶女贞来帮助清除呼吸道(包括喉咙、肺部和支气管)中的粘液。虽然很少有研究对小叶女贞的安全性和有效性进行评估,但一些草药学家将小叶女贞作为哮喘综合治疗方案的一部分。19 世纪时,美国医生曾用这种草药来催吐,以清除体内毒素。然而,由于小叶女贞具有刺激呼吸和祛痰的特性,因此应按照正确的剂量将其与舒缓喉咙和肺部的草药一起使用,而且小叶女贞通常被用于协同草药配方中,其中包括小叶女贞的草药和种子、Zingiber officinale 和 Hyssopus officinalis。在哮喘发作时,该研究物种不应被用作药物治疗的替代品,孕期禁用。叶舌草没有已知的不良药物相互作用,因此是治疗呼吸系统疾病的一种很有前景的辅助疗法,特别是考虑到最近与 Covid-19 相关的呼吸系统疾病的发病率有所上升。总之,目前的研究数据证明了使用该植物治疗因感染 Covid-19 导致的呼吸系统疾病的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lobelia inflata L. as an Alternative Medicine for Respiratory Problems Provoked by Covid- 19: A Review
Lobelia inflata (Indian tobacco, Campanulaceae) is an herbal remedy for many respiratory conditions such as asthma, bronchitis, pneumonia, and cough. The main objective of the current review is to document the potential use of L. inflata as respiratory stimulant in patients suffering from Covid-19 infection. Native Americans smoked the plant as a treatment for asthma and today, lobelia is sometimes suggested to help clear mucus from the respiratory tract, including the throat, lungs, and bronchial tubes. Although few studies have evaluated the safety and effectiveness of lobelia, some herbalists use lobelia as part of a comprehensive treatment plan for asthma. In the 19th century, American physicians prescribed the herb to induce vomiting in order remove toxins from the body. However, because of its properties as a respiratory stimulant and expectorant, the plant should be used at the correct dose and together with herbs that are soothing to the throat and lungs, and it is often used in a synergistic herbal formula that includes L. inflata herb and seed, Zingiber officinale, and Hyssopus officinalis. The study species should not be used as a substitute for drug therapy during an asthma attack and its use is contraindicated during pregnancy. Lobelia inflata has no known adverse drug interactions and it is therefore a promising complementary therapy for the management of respiratory disorders, in particular in light of the recent increase in the prevalence of respiratory diseases associated with Covid-19. In conclusions, data of the current study has proven the possibility of using the plant in treating the respiratory disorders resulting from infection with Covid-19.
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