基于麦芽右旋糖苷浓度差异的 Temulawak(莪术)片剂中的总酚和类黄酮化合物分析

Dina Wahyu Indriani, Nadya Mutiarani, A. Lastriyanto
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摘要

Temulawak (Curcuma xanthorrhiza Roxb.) 具有经验酚类和类黄酮,可作为抗氧化剂。本研究的目的是通过改变麦芽糊精的添加浓度来生产temulawak(Curcuma xanthorrhiza Roxb.)片剂,并找出最佳效果。这项研究采用了非因子随机区组设计(RBD),有三个处理水平,麦芽糊精的比例分别为 1:2(50%)、1:4(25%)和 1:6(16.70%)。 研究结果表明,所有成型片剂均符合 2019 年第 32 号 BPOM 的要求,即片剂必须小于或等于 10%,且所有成型片剂重量均匀。与 1:4(25%)、1:6(16.70%)和对照处理相比,1:2(50%)处理的片剂酚类和类黄酮的平均总值最高。在 1:2 (50%)处理中,总酚值为 3.63 毫克 GAE/g ± 0.09,总类黄酮值为 6.11 毫克 QE/g ± 0.30。因此可以说,在本研究中,麦芽糊精浓度为 1:2(50%)的处理方法是生产 temulawak(莪术)片剂的最佳方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of Total Phenol and Flavonoid Compounds in Temulawak (Curcuma xanthorrhiza Roxb.) Tablets Based on Differences in Maltodextine Concentration
Temulawak (Curcuma xanthorrhiza Roxb.)  has empirical phenolics and flavonoids which can act as antioxidants. The purpose of this study was to produce tablets of temulawak (Curcuma xanthorrhiza Roxb.) with variations in the addition of maltodextrin concentration and to find the best results. This research was conducted using a non-factorial Randomised Block Design (RBD) with 3 treatment levels, the ratio of maltodextrin to 1:2 (50%), 1:4 (25%) and 1:6 (16.70%).  The results of this study showed that all tablets formed met the requirements of BPOM Number 32 of 2019 such that the tablets must be less than or equal to 10% and all the shaped tablets had a uniform weight. The tablets with 1:2 (50%) treatment had the highest value which was able to produce the highest total mean value of phenolics and flavonoids when compared with 1:4 (25%), 1:6 (16,70%) and control treatments. In a 1:2 (50%) treatment, the total phenolic value was 3.63 mg GAE/g ± 0.09, while the total flavonoid value was 6.11 mg QE/g ± 0.30. Therefore, it can be stated that the maltodextrin concentration treatment with a ratio of 1:2 (50%) was the optimum method for producing temulawak (Curcuma xanthorrhiza Roxb.) tablets in this study.
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