维生素 D3 综述:代谢、功能和临床意义

Marwah A. AL-AZZAWI, Anmar .J.Maftool, Anmar A. Al-Shimary, Ali Abdulmawjood Mohammed
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引用次数: 0

摘要

本文探讨了胆钙化醇的新陈代谢、在体内的功能以及与临床的相关性。维生素 D3 或胆钙化醇对许多生理过程都很重要,是人体健康的必需品。这篇综述的目的是首先对维生素 D3 进行广泛的讨论,然后解释它是如何在人体内流动的,以确定为什么维生素 D3 的水平因人而异。文章非常精确地描述了维生素 D3 的功能,包括支持骨骼强度、使血钙水平正常化、免疫调节以及与慢性疾病发病率的关系。文章还讨论了维生素 D3 与肌肉骨骼完整性、心血管功能、精神/心理健康和肿瘤抑制的关系。文章详细评估了维生素 D3 缺乏症的筛查方法,包括诊断、膳食来源和补充制度。最后,文章探讨了在临床工作中添加维生素 D3 的可能性。在考虑与维生素 D3 有关的可能副作用的同时,还进行了安全性评估。这篇综述强调了维生素 D3 在维持人类生命方面的关键作用及其对人口健康管理的重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Comprehensive Review of Vitamin D3: Metabolism, Functions, and Clinical Implications
The current article examines the metabolism of cholecalciferol, its functions in body, and relevance within a clinical set up. Vitamin D3 or cholecalciferol is important for many physiological processes and is essential for general health. The purpose of this review is to begin by providing extensive discussions about vitamin D3 thereafter explain how it travels through the body in order to determine why its level varies from one human to another. The article is very precise describing the functions of vitamin D3 which includes supporting bone strength, normalization of calcium blood levels, immunological regulation, and relation with the chronic disease incidence. The article also discusses how vitamin D3 relates to musculoskeletal integrity, cardiovascular functioning, mental/psychological wellbeing, and tumor inhibition. Vitamin D3 deficiency screening methodology including diagnosis, dietary sources and supplementation regime is assessed in detail. Lastly, the article touches on the potential of adding vitamin D3 in clinical work. Safety assessments are performed while considering possible side effects in relation to vitamin D3. This review underscored the critical role of vitamin D3 in sustaining human life and its significance for population health management.
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