2019年冠状病毒疾病(COVID-19)的不同治疗策略中的健康与福祉:微型综述

L. Abdulazeem, Maryam muwafaq jasim, Noor J.T. AL-Musawi
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摘要

为了实现可持续发展,所有年龄段的人都必须过上健康的生活,增进福祉。COVID-19 正在削弱全球经济,同时也在扰乱全世界数十亿人的生活。到 2019 年底,导致严重急性呼吸系统综合征(SARS-CoV2)的新型冠状病毒突然开始传播,由此产生了 2019 年冠状病毒病(COVID19)一词。目前还没有针对 COVID-19 的行之有效的治疗方法。目前急需找到有效的治疗方法来护理患者并控制 SARS-CoV2 在人类中的传播。本综述强调了可用于抗击 SARS-CoV2 感染的治疗药物。自 COVID19 出现以来,许多药物已被重新用于 COVID19 的治疗。关于 COVID-19 的治疗,除了氯喹(CQ)等现有药物外,我们还研究了单克隆抗体、复原血浆、中草药治疗和天然化合物,包括雷米替韦、羟基氯喹(HCQ)和核苷类似物。尽管最初的临床试验证明 CQ/HCQ 具有抗病毒活性,但进一步的调查显示,对其是否适用于治疗 COVID-19 还存在很大争议。防止病毒与人体细胞的血管紧张素转换酶 2 受体相互作用是这些药物对 SARS-CoV2 的生物防御作用之一。许多关于纳米材料在治疗 Covid-19 方面的作用的研究都是基于纳米材料独特的物理、化学和生物特性,这些特性取决于纳米材料的形状和大小,因为使用纳米材料被认为是消除包括 Covid-19 在内的病毒的一种前景广阔的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Good Health and Well- being in the Different Current Treatment Strategies for Coronavirus Disease 2019 (COVID-19): A mini Review
People of all ages must lead healthy lives and advance wellbeing in order for sustainable development to occur. The global economy is being weakened by COVID-19, which is also disrupting the lives of billions of people worldwide. By the end of 2019, the novel coronavirus that causes severe acute respiratory syndrome (SARS-CoV2) abruptly began to spread, giving rise to the term coronavirus disease 2019 (COVID19). There is currently no proven treatment for COVID-19. Finding efficient therapies is urgently needed to care for patients and control the spread of SARS-CoV2 among humans. The treatment medicines that may be employed to fight the SARS-CoV2 infection were emphasized for the current review. Numerous medications have been repurposed for COVID19 therapy since the disease's emergence. Regarding the treatment of COVID-19, existing medications such as chloroquine (CQ), Along with chloroquine, We also investigated monoclonal antibodies, restorative plasma, Chinese herbal treatment, and natural compounds, including remdesivir, hydroxychloroquine (HCQ), and nucleoside analogues. Although initial clinical trials demonstrated that CQ/HCQ had antiviral activities, further investigations revealed significant debate over its suitability for treating COVID-19. Preventing the virus from interacting with human cell receptors for angiotensin converting enzyme 2 is one of these medicinal medicines' biological defenses against SARS-CoV2. Many of studies about the role of nanomaterials in treating Covid-19, based on their unique physical, chemical and biological properties, which depend on shape and size, as the use of nanomaterials is considered a promising future to eliminate viruses, including Covid-19.
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