地中海贫血症的治疗方案和管理方法概述

Hiba Qasim Mahmoud, Russl Sameer Mhana, Ali Abdulmawjood Mohammed
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引用次数: 0

摘要

地中海贫血症患者体内会产生一种异常形式的血红蛋白,这是一种家族遗传性血液疾病。这种疾病会导致大量红细胞被破坏,从而引起贫血。地中海贫血患者面临的主要问题是铁负荷过重、心律失常、肝炎、骨质疏松症和内分泌失调;不过,贫血也可能表现为常规症状。地中海贫血患者的治疗方案取决于病情的严重程度。地中海贫血症的标准治疗方式是输血。地中海贫血综合征的名称是根据产生的缺陷血红蛋白或受影响的球蛋白链来命名的。因此,β-球蛋白基因突变导致β地中海贫血症,而α-球蛋白基因突变导致α地中海贫血症。本综述涵盖了地中海贫血的各种形式,以及其诊断、发病率、并发症和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Therapeutic options and management approach on thalassemia an overview
People with thalassemia, the body produces an aberrant form of hemoglobin, a hereditary blood condition that runs in families. Anemia is caused by this disorder, which causes a significant number of red blood cells to be destroyed. Iron overload, cardiac arrhythmia, hepatitis, osteoporosis, and endocrine disorders are the primary problems that thalassemia patients confront; however, anemia can also present with conventional symptoms. Treatment options for thalassemia patients are based on how serious their condition is. The standard form of treatment for thalassemia is blood transfusion. The names of thalassemia syndromes are based on the defective hemoglobin produced or the globin chain that is impacted. Thus, Mutations in the β-globin gene result in β-thalassemia, while mutations in the α-globin gene cause α-thalassemia. This review covers the various forms of thalassemia, as well as its diagnosis, prevalence, complications, and management.
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