马来西亚一家三甲医院的听神经瘤手术结果

Siti Sarah Razak, Asma Abdullah, N. Hashim, Azizi Abu Bakar, R. Sutan, Abdullah Sani
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引用次数: 0

摘要

导言:听神经瘤(AN)或前庭分裂瘤是一种良性、生长缓慢的肿瘤,来自前庭神经前庭支的许旺细胞。治疗方法主要是保守治疗或手术切除。本研究旨在描述马来西亚一家三级医院中前庭大腺肿瘤的临床特征和手术效果。材料和方法:研究人员检索了自2008年1月至2019年12月期间被诊断为AN的73名患者的记录。对所有患者的人口统计学数据和临床特征进行了分析。共有52名患者接受了AN手术,术前面神经功能正常。对每位患者的手术结果进行了描述性分析。结果:患者的中位年龄为 51.5 岁(15.8 SD)。74.0%的患者术前听力水平为重度到极重度,15.1%为中度到重度,6.8%为轻度到中度,2.7%为轻度听力损失。最常用的手术方法是后蝶窦入路(48.1%),其次是迷宫内入路(44.2%)和中颅窝入路(7.7%)。与后颅窝和中颅窝入路(40.4%)相比,迷走神经后入路术后面神经瘫痪的发生率最低(21.2%)。然而,手术方法与面神经结果之间并无明显关联(P=0.07)。结论:无论采用哪种手术方式,AN手术都是安全的。肿瘤大小与面神经预后有明显关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical outcome of Acoustic Neuroma Surgery in a Malaysian Tertiary Hospital
INTRODUCTION: Acoustic neuroma (AN) or vestibular schwannoma, is a benign, slow-growing tumour that arises from the Schwann cell of the vestibular branch of the vestibulocochlear nerve. Treatment options are mainly conservative or surgical excision. The aim of this study is to describe the clinical characteristics of AN and the surgical outcomes in a Malaysian tertiary hospital. MATERIALS AND METHOD: Records of 73 patients who were diagnosed with AN from January 2008 until December 2019 were retrieved. All patients were analyzed for demographic data and clinical characteristics. In all 52 patients underwent AN surgery and had normal preoperative facial nerve function. A descriptive analysis was used for the surgical outcomes of each patient. RESULTS: The median age of patients was 51.5 (15.8 SD). Hearing levels pre-operatively were severe to profound in 74.0% of the patients, followed by moderate to severe in 15.1%, mild to moderate in 6.8%, and mild hearing loss in 2.7%. Retrosigmoid (48.1%) was the most common surgical approach used, followed by translabyrinthine (44.2%) and middle cranial fossa (MCF) (7.7%). The translabyrinthine approach is associated with the least incidence of facial nerve paresis postoperatively (21.2%) when compared to the retrosigmoid and middle cranial fossa approaches (40.4%). However, there was no significant association between surgical approaches and facial nerve outcome (p=0.07). CONCLUSION: AN surgery is a safe procedure, regardless of the surgical approach used. There was a significant relationship between tumour size and facial nerve outcome.
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