评估过敏性鼻炎患者对鼻腔类固醇治疗的依从性和态度。

IF 2.3 4区 医学 Q3 ALLERGY
Begum Gorgulu Akin, Irem Kar, Omur Aydin
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引用次数: 0

摘要

背景:过敏性鼻炎(AR)被定义为鼻部炎症性疾病。鼻腔皮质类固醇(NCS)是治疗过敏性鼻炎最有效的药物之一:治疗过敏性鼻炎最重要的问题之一是患者对 NCS 的依从性。我们旨在评估 AR 患者对 NCS 治疗的依从性和态度:研究纳入了 144 名在任何时间开具非化疗药物治疗 AR 并在研究期间使用非化疗药物的患者。对患者进行莫里斯基医疗依从性量表-8(MMAS-8)测试,以确定其治疗依从性:结果:55% 的患者在莫里斯基医疗依从性量表-8 中的得分低于 6 分,患者对非处方药治疗的依从性较低。只有 19% 的患者对非加太治疗的依从性良好。随着病程的延长,患者对治疗的依从性降低(p = 0.001)。从过敏原免疫疗法中获益的患者的 MMAS-8 评分明显高于未获益的患者(p = 0.015)。不出所料,出现药物相关不良反应的患者的服药依从性在统计学上明显较低(p = 0.01)。60%的患者接受过 NCS 培训,接受过培训的患者 MMAS-8 评分明显更高(p = 0.023):结论:服药依从性不足是 AR 治疗中的一个棘手问题。结论:服药依从性不足是治疗 AR 的难题,经常评估患者的服药依从性和日常用药技巧对疾病的随访和治疗非常重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of adherence and attitudes of patients with allergic rhinitis to nasal steroid treatment.

Background: Allergic rhinitis (AR) is defined as an inflammatory disease of the nose. Nasal corticosteroids (NCS) are one of the most effective drugs used in AR treatment.

Objective: One of the most important issues in the treatment of AR is patient adherence to NCS. We aimed to evaluate the adherence and attitude of patients with AR to NCS treatment.

Methods: One hundred four patients who were prescribed NCS for AR at any time and who used NCS during the study period were included in the study. Morisky Medical Adherence Scale-8 (MMAS-8) was performed on the patients to determine their treatment adherence.

Results: The scores of the MMAS-8 were below 6 in 55% of the patients, and the adherence of the patients to the NCS treatment was low. The adherence of the patients to NCS treatment was good in only 19% of the patients. As the duration of the disease increased, the adherence of the patients to the treatment decreased (p = 0.001). Patients who benefited from allergen immunotherapy had statistically significantly higher MMAS-8 scores than those who did not (p = 0.015). As expected, drug adherence was statistically significantly lower in patients with drug-related adverse effects (p = 0.01). Sixty percent of the patients had received NCS training, and MMAS-8 scores were significantly higher in those who received training (p = 0.023).

Conclusion: Inadequate drug adherence is a challenging problem in the treatment of AR. Frequent evaluation of patients' drug adherence and drug use techniques in daily practice is important for the follow-up and treatment of the disease.

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来源期刊
CiteScore
12.80
自引率
0.00%
发文量
74
审稿时长
>12 weeks
期刊介绍: The Asian Pacific Journal of Allergy and Immunology (APJAI) is an online open access journal with the recent impact factor (2018) 1.747 APJAI published 4 times per annum (March, June, September, December). Four issues constitute one volume. APJAI publishes original research articles of basic science, clinical science and reviews on various aspects of allergy and immunology. This journal is an official journal of and published by the Allergy, Asthma and Immunology Association, Thailand. The scopes include mechanism, pathogenesis, host-pathogen interaction, host-environment interaction, allergic diseases, immune-mediated diseases, epidemiology, diagnosis, treatment and prevention, immunotherapy, and vaccine. All papers are published in English and are refereed to international standards.
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