腹胀患者的疾病谱和自然史:纵向研究

IF 3.3 3区 医学 Q2 CLINICAL NEUROLOGY
Fangfei Chen, Niandi Tan, Songfeng Chen, Qianjun Zhuang, Mengyu Zhang, Yinglian Xiao
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引用次数: 0

摘要

背景/目的:腹胀(AB/D)是消化内科门诊的常见病。由于潜在的致病因素众多且复杂,为了更好地了解 AB/D 的关键因素,我们对患者的疾病谱和自然史进行了纵向研究:方法:对门诊转诊的主诉为 AB/D 的连续患者进行筛查。根据罗马IV标准诊断为功能性胃肠病(FGID)。进行为期 3 年的随访,以了解症状和疾病谱的变化:结果:共有 261 人参加了随访,其中 139 人完成了随访。大多数患者每周出现中度至重度症状超过 1 天。AB/D的常见病因是FGID(51.7%)和器质性疾病(17.2%)。后者年龄较大,体重指数(BMI)较低。功能性消化不良是 AB/D 最常见的 FGIDs 类型。18.0%的参与者的症状在3年随访结束时没有得到改善,而那些被诊断为功能性消化不良的人最有可能继续遭受痛苦。腹痛是 FGIDs 组预后良好的积极预测因素。此外,只有22.7%的参与者在随访期间被一致诊断为FGIDs:结论:FGID 是 AB/D 患者最常见的诊断。结论:FGID 是 AB/D 患者最常见的诊断,其症状尤其难以改善。AB/D患者的FGID分类诊断随着时间的推移波动很大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Disease Spectrum and Natural History of Patients With Abdominal Bloating or Distension: A Longitudinal Study.

Background/aims: Abdominal bloating or distension (AB/D) is a common complaint in the outpatient of gastroenterology department. Since the potential contributors are numerous and complex, a longitudinal study on the disease spectrum and natural history of patients was performed to better understand the key factors of AB/D.

Methods: Consecutive patients with the chief complaint of AB/D referred to the outpatient clinic were screened. Functional gastrointestinal disorders (FGIDs) were diagnosed according to Rome IV criteria. A 3-year follow-up was performed to seek for the changes in symptoms as well as disease spectrum.

Results: A total of 261 participants were enrolled and 139 completed the follow-up. Most patients suffered from moderate to severe symptoms more than 1 day per week. Common causes of AB/D were FGIDs (51.7%) and organic diseases (17.2%). The latter group was older with lower body mass index (BMI). Functional dyspepsia was the most common type of FGIDs in AB/D. The symptoms of 18.0% of participants failed to improve at the end of the 3-year follow-up, and those diagnosed with FGIDs were most likely to continue to suffer. Abdominal pain was a positive predictive factor for good prognosis in the FGIDs group. Besides, only 22.7% of participants had a consistent diagnosis of FGIDs during follow-up.

Conclusions: FGIDs are the most common diagnosis in patients with AB/D. Symptoms were especially hard to be improved. Classification diagnoses of FGIDs in AB/D patients fluctuated significantly over time.

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来源期刊
Journal of Neurogastroenterology and Motility
Journal of Neurogastroenterology and Motility GASTROENTEROLOGY & HEPATOLOGY-CLINICAL NEUROLOGY
CiteScore
6.30
自引率
8.80%
发文量
96
期刊介绍: Journal of Neurogastroenterology and Motility (J Neurogastroenterol Motil) is a joint official journal of the Korean Society of Neurogastroenterology and Motility, the Thai Neurogastroenterology and Motility Society, the Japanese Society of Neurogastroenterology and Motility, the Indian Motility and Functional Disease Association, the Chinese Society of Gastrointestinal Motility, the South East Asia Gastro-Neuro Motility Association, the Taiwan Neurogastroenterology and Motility Society and the Asian Neurogastroenterology and Motility Association, launched in January 2010 after the title change from the Korean Journal of Neurogastroenterology and Motility, published from 1994 to 2009.
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