用于免疫工程的治疗合成材料和天然材料

IF 39 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Anna Slezak, Kevin Chang, Samir Hossainy, Aslan Mansurov, Stuart J. Rowan, Jeffrey A. Hubbell and Mustafa O. Guler
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引用次数: 0

摘要

免疫工程是一个快速发展的领域,它推动了操纵免疫系统以获得新的治疗工具和方法的创新。近年来,由于对针对和调节免疫系统的有效疗法的需求日益增长,免疫工程应用对材料的需求得到了极大关注。生物制剂和生物材料正在成为控制免疫反应的有前途的工具,目前正在为此开发各种各样的材料,包括蛋白质、聚合物、纳米颗粒和水凝胶。在这篇综述文章中,我们将探讨用于免疫工程应用的不同类型材料、它们的特性和设计原理,并重点介绍最新的治疗材料进展。文章还讨论了佐剂、疫苗、免疫耐受、免疫疗法和用于免疫工程研究的组织模型等方面的最新研究成果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Therapeutic synthetic and natural materials for immunoengineering

Therapeutic synthetic and natural materials for immunoengineering

Therapeutic synthetic and natural materials for immunoengineering

Immunoengineering is a rapidly evolving field that has been driving innovations in manipulating immune system for new treatment tools and methods. The need for materials for immunoengineering applications has gained significant attention in recent years due to the growing demand for effective therapies that can target and regulate the immune system. Biologics and biomaterials are emerging as promising tools for controlling immune responses, and a wide variety of materials, including proteins, polymers, nanoparticles, and hydrogels, are being developed for this purpose. In this review article, we explore the different types of materials used in immunoengineering applications, their properties and design principles, and highlight the latest therapeutic materials advancements. Recent works in adjuvants, vaccines, immune tolerance, immunotherapy, and tissue models for immunoengineering studies are discussed.

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来源期刊
Chemical Society Reviews
Chemical Society Reviews 化学-化学综合
CiteScore
80.80
自引率
1.10%
发文量
345
审稿时长
6.0 months
期刊介绍: Chemical Society Reviews is published by: Royal Society of Chemistry. Focus: Review articles on topics of current interest in chemistry; Predecessors: Quarterly Reviews, Chemical Society (1947–1971); Current title: Since 1971; Impact factor: 60.615 (2021); Themed issues: Occasional themed issues on new and emerging areas of research in the chemical sciences
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