布洛克-陶西格分流术与导管支架植入术作为导管依赖性肺循环的姑息治疗方法。

Q3 Medicine
Sultan Qaboos University Medical Journal Pub Date : 2023-12-01 Epub Date: 2023-11-30 DOI:10.18295/squmj.12.2023.073
Hamood Al Kindi, Hasina Al Harthi, Asim Al Balushi, Ahlam Atiq, Samiuddin Shaikh, Khalid Al Alawi, Abdullah Al-Farqani
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引用次数: 0

摘要

目的:北美和欧洲以外地区发表的比较改良布洛克-陶西格分流术(MBTS)和导管支架植入术作为导管依赖性肺循环婴儿首次姑息手术的结果的数据非常有限。本研究报告了阿曼马斯喀特国家心脏中心在比较这两种干预方法疗效方面的经验:这项回顾性研究纳入了 2016-2019 年期间接受 MBTS 或导管支架植入术的所有导管依赖性肺循环婴儿。主要结果为死亡或再次干预。次要结果包括死亡、后续再次干预、后续手术干预存活率、出院存活率、术后机械通气和重症监护室住院时间:共有 71 名患者参与研究,其中 33 人(46%)接受了导管支架植入术。动脉导管未闭(PDA)支架组的主要结果(死亡或再次介入)发生率为 54.5%,而 MBTS 组为 31.6%,但差异无统计学意义(P = 0.06)。就下一次手术干预的时间而言,两组之间没有差异(P = 0.233)。PDA 支架组的术后、机械通气和重症监护室住院时间更短(P 结论:PDA 支架组的术后、机械通气和重症监护室住院时间更短(P = 0.06):MBTS和导管支架植入术都是可接受的肺循环导管依赖性婴儿姑息干预方式。综合征患者的死亡风险较高。这也是选择患者的一个重要因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Blalock-Taussig Shunt versus Ductal Stenting as Palliation for Duct-Dependent Pulmonary Circulation.

Objectives: There is limited data published from outside North America and Europe comparing the outcomes of a modified Blalock-Taussig shunt (MBTS) and ductal stenting as the first palliative procedure for infants with duct-dependent pulmonary circulation. This study reports the National Heart Center's, in Muscat, Oman, experience in comparing the outcomes of these 2 interventions.

Methods: This retrospective study included all infants with duct-dependent pulmonary circulation who received either a MBTS or ductal stenting from 2016-2019. The primary outcomes were death or re-interventions. Secondary outcomes included death, subsequent re-interventions, survival to subsequent surgical intervention, survival to hospital discharge, post-procedural mechanical ventilation and duration of intensive care unit stay.

Results: A total of 71 patients were included in the study, 33 (46%) of whom received ductal stenting. The prevalence of the primary outcome (death or re-intervention) in the patent ductus arteriosus (PDA) stent group was 54.5% versus 31.6% in the MBTS group but this was not statistically significant (P = 0.06). There was no difference between the 2 groups in terms of time to next surgical intervention (P = 0.233). The PDA stent group had shorter post-procedural, mechanical ventilation and intensive care unit stay durations (P <0.05). Syndromic patients were at higher risk of mortality compared to non-syndromic patients.

Conclusion: MBTS and ductal stenting are both acceptable modalities as a palliative intervention for infants with duct-dependant pulmonary circulation. Syndromic patients are at higher risk of mortality. This can be considered an important factor for patient selection.

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CiteScore
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自引率
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