作为多发性硬化症首发表现的急性双侧肌张力减退和内斜视综合征：病例报告。

IF 0.9 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Nagoya Journal of Medical Science Pub Date : 2023-11-01 DOI:10.18999/nagjms.85.4.822

Joe Senda, Ryota Hirao, Kentaro Maeda, Yoshinobu Amakusa, Tomoki Hirunagi, Masahisa Katsuno, Katsuhiro Kawaguchi

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引用次数: 0

摘要

一名 21 岁的日本女性突然出现眼球运动障碍。眼科检查发现双侧眼球下垂和内斜复合体。脑磁共振成像显示，下脑桥后部和内侧部分（包括脑室周围和皮质下白质）出现异常信号，提示脱髓鞘。脑脊液检测呈寡克隆带阳性。随后，她被诊断为多发性硬化症，并接受了甲基强的松龙静脉注射和富马酸二甲酯口服治疗，两个月后，低视和内斜完全恢复。双侧视力低下和内斜视是准确诊断多发性硬化症的重要临床表现。

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Acute bilateral hypotropia and esotropia complex as first manifestation of multiple sclerosis: a case report.

A 21-year-old Japanese woman presented with sudden eye movement disorders. An ophthalmic examination revealed bilateral hypotropia and esotropia complex. Brain magnetic resonance imaging revealed abnormal signals in the posterior and medial part of the lower pontine tegmentum (including periventricular and subcortical white matter) that were suggestive of demyelination. A cerebrospinal fluid test was positive for oligoclonal bands. She was subsequently diagnosed with multiple sclerosis and was administered intravenous methylprednisolone and oral dimethyl fumarate, with complete recovery from hypotropia and esotropia after two months. Bilateral hypotropia and esotropia are important clinical signs for the accurate diagnosis of multiple sclerosis.

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来源期刊

Nagoya Journal of Medical Science MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal publishes original papers in the areas of medical science and its related fields. Reviews, symposium reports, short communications, notes, case reports, hypothesis papers, medical image at a glance, video and announcements are also accepted. Manuscripts should be in English. It is recommended that an English check of the manuscript by a competent and knowledgeable native speaker be completed before submission.