{"title":"通过结合单脉冲和固体回波实验以及全局模型拟合分析,探测核磁共振中的 \"死区时间","authors":"Eddy Walther Hansen","doi":"10.1007/s00723-023-01637-5","DOIUrl":null,"url":null,"abstract":"<div><p>The main question addressed in this work is how to probe the “effective dead-time” in an NMR instrument, i.e., the time needed to blank the receiver after an rf-pulse excitation to prevent damage to the receiver and to avoid any distortion of the NMR signal being sampled. The strategy is to design a suitable FID-model to fit the single pulse excitation (SPE) and solid echo pulse (SEPS) data (on solid Tricosane) using a Global model-fit analysis technique. The derived dead time is discussed with respect to sampling temperature (25–40 °C) and—in particular—with respect to the number of SEPS data involved in the Global fit analysis by applying the Bayesian Information Criterion (BIC) in combination with more traditional statistical analysis. It is concluded that the “effective dead time” can be determined within a standard error of less than 2.5%.</p></div>","PeriodicalId":469,"journal":{"name":"Applied Magnetic Resonance","volume":"55 4","pages":"477 - 496"},"PeriodicalIF":1.1000,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00723-023-01637-5.pdf","citationCount":"0","resultStr":"{\"title\":\"Probing the “Dead-Time” in NMR by Combining Single Pulse and Solid Echo Experiments Followed by a Global Model Fit Analysis\",\"authors\":\"Eddy Walther Hansen\",\"doi\":\"10.1007/s00723-023-01637-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The main question addressed in this work is how to probe the “effective dead-time” in an NMR instrument, i.e., the time needed to blank the receiver after an rf-pulse excitation to prevent damage to the receiver and to avoid any distortion of the NMR signal being sampled. The strategy is to design a suitable FID-model to fit the single pulse excitation (SPE) and solid echo pulse (SEPS) data (on solid Tricosane) using a Global model-fit analysis technique. The derived dead time is discussed with respect to sampling temperature (25–40 °C) and—in particular—with respect to the number of SEPS data involved in the Global fit analysis by applying the Bayesian Information Criterion (BIC) in combination with more traditional statistical analysis. It is concluded that the “effective dead time” can be determined within a standard error of less than 2.5%.</p></div>\",\"PeriodicalId\":469,\"journal\":{\"name\":\"Applied Magnetic Resonance\",\"volume\":\"55 4\",\"pages\":\"477 - 496\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2023-12-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://link.springer.com/content/pdf/10.1007/s00723-023-01637-5.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Magnetic Resonance\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00723-023-01637-5\",\"RegionNum\":4,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHYSICS, ATOMIC, MOLECULAR & CHEMICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Magnetic Resonance","FirstCategoryId":"101","ListUrlMain":"https://link.springer.com/article/10.1007/s00723-023-01637-5","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHYSICS, ATOMIC, MOLECULAR & CHEMICAL","Score":null,"Total":0}
Probing the “Dead-Time” in NMR by Combining Single Pulse and Solid Echo Experiments Followed by a Global Model Fit Analysis
The main question addressed in this work is how to probe the “effective dead-time” in an NMR instrument, i.e., the time needed to blank the receiver after an rf-pulse excitation to prevent damage to the receiver and to avoid any distortion of the NMR signal being sampled. The strategy is to design a suitable FID-model to fit the single pulse excitation (SPE) and solid echo pulse (SEPS) data (on solid Tricosane) using a Global model-fit analysis technique. The derived dead time is discussed with respect to sampling temperature (25–40 °C) and—in particular—with respect to the number of SEPS data involved in the Global fit analysis by applying the Bayesian Information Criterion (BIC) in combination with more traditional statistical analysis. It is concluded that the “effective dead time” can be determined within a standard error of less than 2.5%.
期刊介绍:
Applied Magnetic Resonance provides an international forum for the application of magnetic resonance in physics, chemistry, biology, medicine, geochemistry, ecology, engineering, and related fields.
The contents include articles with a strong emphasis on new applications, and on new experimental methods. Additional features include book reviews and Letters to the Editor.