对日本肝胆胰外科委员会认证专家和导师进行的关于肝细胞癌手术适应症的问卷调查。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
Keiichi Akahoshi, Junichi Shindoh, Minoru Tanabe, Shuichi Watanabe, Hayato Takamizawa, Susumu Eguchi, Itaru Endo, Shoji Kubo, Akinobu Taketomi, Hiroaki Nagano, Masafumi Nakamura, Kiyoshi Hasegawa, Etsuro Hatano, Tomoharu Yoshizumi, Norihiro Kokudo
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引用次数: 0

摘要

背景:肝细胞癌(HCC)全身治疗的最新进展要求建立晚期 HCC 可切除性标准:肝细胞癌(HCC)系统治疗的最新进展要求制定晚期 HCC 的可切除性标准:一项问卷调查旨在明确日本肝胆外科医生对 HCC 手术适应症的看法。31个问题用于确定何时强烈建议手术(可切除:R)或不建议手术(不可切除:UR):结果:共收到 351 份回复。64.7%的受访者认为单发肿瘤无论大小均为 R,但对于 R 的肿瘤数量/肿瘤大小上限则意见不一:(1) 最多 3 个结节,大小不限(27.9%);(2) 最多 3 个结节,每个直径≤5 厘米(21.4%);(3) 最多 3 个结节,每个直径≤3 厘米(19.4%)。分别有 90.9%、70.7%、39.0% 和 8.0%的受访者认为 Vp1、Vp2、Vp3 和 Vp4 为 R。半数受访者表示,即使是肝外扩散的病例,他们也会在有限的条件下考虑切除:结论:日本外科医生专家目前对 HCC 可切除标准的看法首次得到了澄清。这些研究结果可作为编写关于 HCC 可切除标准的专家共识声明的基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Questionnaire survey of Japanese board-certified expert hepatobiliary and pancreatic surgeons and instructors on the surgical indications for hepatocellular carcinoma

Questionnaire survey of Japanese board-certified expert hepatobiliary and pancreatic surgeons and instructors on the surgical indications for hepatocellular carcinoma

Background

Recent advancements in systemic therapy for hepatocellular carcinoma (HCC) necessitate the establishment of resectability criteria for advanced HCC.

Methods

A questionnaire survey sought to clarify the perspectives of Japanese expert hepatobiliary surgeons regarding surgical indications for HCC. Thirty-one questions were used to determine when surgery is strongly recommended (resectable: R) or not recommended (unresectable: UR).

Results

A total of 351 responses were obtained. While 64.7% of the respondents considered solitary tumors as being R, irrespective of size, opinions diverged on the upper limit of the number of tumors/tumor size for R: (1) up to three nodules with no size limit (27.9%), (2) up to three nodules ≤5 cm in diameter each (21.4%) and (3) up to three nodules ≤3 cm in diameter each (19.4%). Vp1, Vp2, Vp3, and Vp4 were considered as being R by 90.9%, 70.7%, 39.0%, and 8.0% of respondents, respectively. Half of the respondents indicated they would consider resection even for cases with extrahepatic spread under limited conditions.

Conclusions

The current views of Japanese expert surgeons on the resectability criteria for HCC were clarified for the first time. The findings could serve as a basis for preparing expert consensus statements on the resectability criteria for HCC.

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CiteScore
7.20
自引率
4.30%
发文量
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