基于纳米技术的创新癌症治疗方法初见端倪：壳聚糖（CS）/聚乙烯醇（PVA）薄膜负载合成的双噻唑衍生物用于癌症治疗

IF 1.1 Q3 CHEMISTRY, MULTIDISCIPLINARY

Egyptian Journal of Chemistry Pub Date : 2023-12-01 DOI:10.21608/ejchem.2023.243862.8757

Manar Ayman, Sobhi M. Gomha, Magda Abdallah, doaa ElNashar, AbdelMohsen Soliman, Huda R. M. Rashdan

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引用次数: 0

摘要

乙酰基噻唑硫代氨基脲 3 被用作关键中间体，通过与两种肼酰卤反应，制备出一系列新型噻唑肼基噻唑衍生物。此外，化合物 3 与 α-卤酮和α-卤酯在乙醇或含有无水乙酸钠的乙酸中，在回流条件下发生反应，得到另一种新的噻唑类化合物。加入

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In Sight into Innovative Cancer Therapeutic Approach Based on Nanotechnology: Chitosan (CS) / Polyvinyl alcohol (PVA) Films loaded with Synthesized Bisthiazole Derivative for Cancer Treatment

Acetyl thiazole thiosemicarbazone 3 was used as key intermediate for preparation of novel series of thiazolylhydrazono thiazole derivatives via reaction of 3 with two types of hydrazonoyl halides. Also, compound 3 reacted with α-haloketones and α-haloester in ethanol or in acetic acid containing anhydrous sodium acetate under reflux to give another new thiazole based compounds. Addionally, the

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来源期刊

Egyptian Journal of Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

2.40

自引率

23.10%

发文量

977

期刊介绍： The Egyptian Journal of Chemistry is published bimonthly by the Egyptian Chemical Society. Contributions from fields of pure chemistry are invited. The fields includes general and physical chemistry, analytical and inorganic chemistry, organic and biological chemistry, and applied and materials chemistry.