颌下腺淀粉样变性：结节外边缘淋巴瘤的罕见表现--病例报告和文献综述

Q3 Dentistry

Oral and Maxillofacial Surgery Cases Pub Date : 2023-12-20 DOI:10.1016/j.omsc.2023.100342

N. Chargi , T. Verhoeven , E. Dik , C. Coppen , L.L. van den Hoogen , W.B.C. Stevens , K.M. Hebeda , W. Weijs

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引用次数: 0

摘要

颌下腺淀粉样变性是结外边缘区淋巴瘤（eMZL）的一种罕见表现。本文报告了一例62岁女性患者的病例，她患有eMZL，局限性IIEA期。患者最初接受了放疗，但大腺体残留对放疗缺乏临床反应。因此，患者接受了颌下腺手术切除，组织学检查发现腺体组织中有大量淀粉样蛋白沉积，旁边还有 eMZL。本病例报告强调了将淀粉样变性视为有淋巴瘤病史的患者颌下腺肿大的可能原因的重要性，并强调了组织学诊断对指导适当治疗的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Submandibular gland amyloidosis: A rare manifestation of extranodal marginal lymphoma – A case report and literature review

Amyloidosis of the submandibular gland is a rare manifestation of extranodal marginal zone lymphoma (eMZL). Here, we present a case-report of a 62-year-old female patient with a history of eMZL, limited stage IIEA. The patient was initially treated with radiotherapy; however large glands remained with lack of clinical response to the radiotherapy. Consequently, a surgical excision of the submandibular glands was performed, and histology revealed massive amyloid deposits in the gland tissue next to eMZL. This case report highlights the importance of considering amyloidosis as a possible cause of submandibular gland enlargement in patients with a history of lymphoma and emphasizes the need for a histological diagnosis to direct appropriate treatment.

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来源期刊

Oral and Maxillofacial Surgery Cases Medicine-Otorhinolaryngology

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

69 days

期刊介绍： Oral and Maxillofacial Surgery Cases is a surgical journal dedicated to publishing case reports and case series only which must be original, educational, rare conditions or findings, or clinically interesting to an international audience of surgeons and clinicians. Case series can be prospective or retrospective and examine the outcomes of management or mechanisms in more than one patient. Case reports may include new or modified methodology and treatment, uncommon findings, and mechanisms. All case reports and case series will be peer reviewed for acceptance for publication in the Journal.