痴呆症药物的成本效益

Nikita Khera, Rojin G Raj, Ranjeet Kumar, Megha Bajaj, Bintoo Sharma, Harsh Tyagi, Josmy Maria Job
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引用次数: 0

摘要

目的:本综述对现有的有关痴呆症药物治疗费用的研究进行了审查和整理。目的:美金刚是一种对 NMDA(N-甲基-D-天冬氨酸)受体具有中低度亲和力的非竞争性拮抗剂,已被批准用于治疗轻度至中度重度阿尔茨海默病(AD)。胆碱酯酶抑制剂(ChEIs)治疗痴呆症的疗效因药物类型和给药难易程度而异。评估痴呆症患者生活质量(QOL)的方法有很多。QOL 数据是衡量干预效果的一个行之有效的指标。迄今为止,成本效益研究主要集中在药物疗法和非药物疗法上。方法:借助以往发表在期刊上的文章,从谷歌学术网站上搜索痴呆症或阿尔茨海默氏症的名称,并与药物经济学或成本和效果交叉引用,观察有关痴呆症药物对药物经济学影响的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cost-effectiveness of Dementia Medication
Aim: This review has examined and organized the available research on dementia medication care costs. Although the accessible database in this area is growing and is still quite limited, there are many clear scientific methods. Objective: The use of Memantine, a non-competitive antagonist with low to moderate affinity for the NMDA (N-methyl-D-aspartate) receptor, has been approved for the treatment of mild to moderately severe Alzheimer's disease (AD). The efficacy of cholinesterase inhibitors (ChEIs) in the treatment of dementia varies depending on the drug type and ease of administration. Numerous techniques have been employed to evaluate the quality of life (QOL) of individuals suffering from dementia. QOL data is a well-established measure of an intervention's effectiveness. Up to now, cost-effectiveness studies have concentrated on both pharmaceutical and non-pharmacological therapy. Each unit of QoL-AD improvement costs USD27.82578 at mean values. Methods: Searches were conducted to observe studies of the pharmacoeconomic impact of dementia medications with the help of previous articles published in journals and collected from Google Scholar with name search dementia or Alzheimer's cross-referenced with pharmacoeconomic or costs and effectiveness.
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